An Arg-Gly-Asp sequence within thrombin promotes endothelial cell adhesion
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Thrombin stimulates fibroblast procollagen production via proteolytic activation of protease-activated receptor 1ADAM 23/MDC3, a human disintegrin that promotes cell adhesion via interaction with the alphavbeta3 integrin through an RGD-independent mechanismThe refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationshipsCollagen nanofibres are a biomimetic substrate for the serum-free osteogenic differentiation of human adipose stem cells.Interaction with glycosaminoglycans is required for cyclophilin B to trigger integrin-mediated adhesion of peripheral blood T lymphocytes to extracellular matrixAngiotensin converting enzyme (ACE) and ACE2 bind integrins and ACE2 regulates integrin signalling.RGD-dependent binding of procathepsin X to integrin alphavbeta3 mediates cell-adhesive properties.Endothelial cell spreading on fibrin requires fibrinopeptide B cleavage and amino acid residues 15-42 of the beta chain.Thrombin as a multifunctional protein: induction of cell adhesion and proliferation.Plasminogen activation in the injured lung: pulmonology does not recapitulate hematology.Thrombin adhesive properties: induction by plasmin and heparan sulfateActivation of alphaVbeta3 on vascular cells controls recognition of prothrombinDisulfides modulate RGD-inhibitable cell adhesive activity of thrombospondinThrombin.Angiogenin supports endothelial and fibroblast cell adhesionPartial characterization of vertebrate prothrombin cDNAs: amplification and sequence analysis of the B chain of thrombin from nine different species.Structural and functional analysis of the globular domain IVa of the laminin alpha 1 chain and its impact on an adjacent RGD site.alphavbeta3 integrin mediates the cell-adhesive capacity and biological activity of basic fibroblast growth factor (FGF-2) in cultured endothelial cells.Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repressionPAR1-dependent and independent increases in COX-2 and PGE2 in human colonic myofibroblasts stimulated by thrombin.Roles of integrins and fibronectin in the entry of Streptococcus pyogenes into cells via protein F1.Proteolytic signatures define unique thrombin-derived peptides present in human wound fluid in vivo.On the mechanism of thrombin-induced angiogenesis: involvement of alphavbeta3-integrin.Spatial and temporal relationships between cadherins and PECAM-1 in cell-cell junctions of human endothelial cellsCatalytically competent human and bovine zeta-thrombin and chimeras generated from unfolded polypeptide chains.RGD peptides and monoclonal antibodies, antagonists of alpha(v)-integrin, enter the cells by independent endocytic pathways.Thrombin functions through its RGD sequence in a non-canonical conformation.RGD-dependent binding of TP508 to integrin alphavbeta3 mediates cell adhesion and induction of nitric oxide.The contributions of integrin affinity and integrin-cytoskeletal engagement in endothelial and smooth muscle cell adhesion to vitronectin.
P2860
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P2860
An Arg-Gly-Asp sequence within thrombin promotes endothelial cell adhesion
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
An Arg-Gly-Asp sequence within thrombin promotes endothelial cell adhesion
@ast
An Arg-Gly-Asp sequence within thrombin promotes endothelial cell adhesion
@en
type
label
An Arg-Gly-Asp sequence within thrombin promotes endothelial cell adhesion
@ast
An Arg-Gly-Asp sequence within thrombin promotes endothelial cell adhesion
@en
prefLabel
An Arg-Gly-Asp sequence within thrombin promotes endothelial cell adhesion
@ast
An Arg-Gly-Asp sequence within thrombin promotes endothelial cell adhesion
@en
P2093
P2860
P356
P1476
An Arg-Gly-Asp sequence within thrombin promotes endothelial cell adhesion
@en
P2093
I Vlodavsky
J W Fenton
M G Lampugnani
P C Marchisio
R Bar-Shavit
P2860
P304
P356
10.1083/JCB.112.2.335
P407
P577
1991-01-01T00:00:00Z