Identification of a thrombin sequence with growth factor activity on macrophages.
about
The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segmentExogenous thrombin delivery promotes collateral capillary arterialization and tissue reperfusion in the murine spinotrapezius muscle ischemia model.Mast cell tryptase is a mitogen for cultured fibroblasts.Identification of a synthetic nonapeptide sequence that inhibits motility in culture of a melanoma subclone that possesses a high metastatic potential.Haemostatic system in inflammatory bowel diseases: new players in gut inflammation.Protease-activated receptor (PAR)-independent growth and pro-inflammatory actions of thrombin on human cultured airway smooth muscle.Formation of factor Va by atherosclerotic rabbit aorta mediates factor Xa-catalyzed prothrombin activationEnhancement of incisional wound healing and neovascularization in normal rats by thrombin and synthetic thrombin receptor-activating peptides.Thrombin as a multifunctional protein: induction of cell adhesion and proliferation.Plasminogen activation in the injured lung: pulmonology does not recapitulate hematology.Proteinase-mediated cell signalling: targeting proteinase-activated receptors (PARs) by kallikreins and more.An Arg-Gly-Asp sequence within thrombin promotes endothelial cell adhesionPartial characterization of vertebrate prothrombin cDNAs: amplification and sequence analysis of the B chain of thrombin from nine different species.Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more.The Yin-Yang of thrombin and activated protein C.Modeling thrombin generation: plasma composition based approach.Heparin cofactor II activation by dermatan sulfate.Coagulation and the expression of cell-mediated immunity.Binding of thrombin to subendothelial extracellular matrix. Protection and expression of functional properties.PAR1-dependent and independent increases in COX-2 and PGE2 in human colonic myofibroblasts stimulated by thrombin.The N-terminal thrombin receptor fragment SFLLRN, but not catalytically inactive thrombin-derived agonists, activate U937 human monocytic cells: evidence for receptor hydrolysis in thrombin-dependent signalling.Thrombin induces endothelial cell growth via both a proteolytic and a non-proteolytic pathway.Roles for thrombin and fibrin(ogen) in cytokine/chemokine production and macrophage adhesion in vivo.Thrombin-stimulated events in cultured vascular smooth-muscle cells.Macrophages activated by fibrin increase albumin permeability across pulmonary artery endothelial monolayers.Restoring hemostatic thrombin generation at the time of cutaneous wounding does not normalize healing in hemophilia B.Animal models of bleeding and tissue repair.Tryptase activates phosphatidylinositol 3-kinases proteolytically independently from proteinase-activated receptor-2 in cultured dog airway smooth muscle cells.The non-proteolytically active thrombin peptide TP508 stimulates angiogenic sprouting.Thrombin stimulates activation of the cerebral 5-lipoxygenase pathway during blood-brain cell contact.Acceleration of full-thickness wound healing in normal rats by the synthetic thrombin peptide, TP508.
P2860
Q27700069-630E5F63-58C8-461C-94C6-B76BC0738608Q30422672-93E3F4C2-A027-4034-B20A-3FD7D33315C6Q34192723-7599E9CC-987C-4103-979B-CDAF2D608B07Q34378256-69CCC85D-9E21-4DAF-91D5-9D7BE41DA5D8Q34579752-0ED4A1F1-D5CE-4B4D-A56E-368661ADA4A2Q35045029-9D88F0FB-BE22-47E6-865E-291F8D5BBE2AQ35590221-18137697-8D5A-488E-A186-D8408C1CA8B2Q35601886-04D23F79-E887-4A4F-B98A-61EB24688205Q35898289-01236F5D-CF97-4FB6-9A1C-EEEAA07466FFQ35898293-CC4055CF-207E-4715-B856-501BBCBC7264Q36519368-036FCCC7-C9CE-4430-B0B3-FD430DAB4382Q36529134-02E10AE0-A50E-4DF9-B5FF-CE26EA4C761BQ36921502-39DBAFBB-4FD0-414B-B3BC-372422FE8896Q37024500-FF54AED5-3E80-4599-8323-B0B9A09F0865Q37084859-4E3A1AFB-A10C-4942-A88F-7302CE9F8DABQ38161459-F02A3E79-1E11-40B2-B847-B7518B30DB99Q38647573-9C0C2BAA-D28E-4E11-B929-72EE70124C17Q39662821-FC7E1F2C-478D-402C-8FB8-9FEF8C56447AQ40511637-72C91EC0-131C-4DD5-8E5A-7D5EF283A4D3Q40680293-84F247FB-E0BC-441A-BAE9-17F3084DDF84Q41837271-1DF46D37-DDB8-4CDF-9DCB-4B75EBA95794Q42004445-C3D62D96-B3F2-4D8D-BDDA-E0B6EA8B3B7BQ42044945-BA35E9F2-8DF7-4981-9C23-5AD2DAA8B8ADQ42627412-14D094DA-1934-4142-9566-E4B292439DCAQ45137619-CCD018BA-3E0F-4B1F-BCBB-6396BC064EA0Q45869844-403001FA-F071-4FE3-A153-F93A208022FBQ45877951-BAE4A59F-446C-458B-BECE-B8C7CDE25081Q46245004-46DEAD28-2B09-40B8-B7E1-DE0A5AE25F61Q46602316-9C4DCEDD-0C64-4FF0-99C6-7931075167F3Q48968866-C70F4414-184A-4410-86EF-1D09493CE89EQ53908855-769919D7-BC43-4D0F-92AF-4F2862D5DB16
P2860
Identification of a thrombin sequence with growth factor activity on macrophages.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Identification of a thrombin sequence with growth factor activity on macrophages.
@ast
Identification of a thrombin sequence with growth factor activity on macrophages.
@en
type
label
Identification of a thrombin sequence with growth factor activity on macrophages.
@ast
Identification of a thrombin sequence with growth factor activity on macrophages.
@en
prefLabel
Identification of a thrombin sequence with growth factor activity on macrophages.
@ast
Identification of a thrombin sequence with growth factor activity on macrophages.
@en
P2093
P2860
P356
P1476
Identification of a thrombin sequence with growth factor activity on macrophages.
@en
P2093
P2860
P304
P356
10.1073/PNAS.83.4.976
P407
P577
1986-02-01T00:00:00Z