Leber's hereditary optic neuropathy: a multifactorial disease.
about
Loss of functional OPA1 unbalances redox state: implications in dominant optic atrophy pathogenesisRecombinant mitochondrial transcription factor A with N-terminal mitochondrial transduction domain increases respiration and mitochondrial gene expression.Multiplex expression cloning of blood-brain barrier membrane proteinsOPA1-related dominant optic atrophy is not strongly influenced by mitochondrial DNA background.Mitochondrial DNA sequence variation and haplogroup distribution in Chinese patients with LHON and m.14484T>CIdentification of novel mitochondrial mutations in Leber's hereditary optic neuropathyMitochondrial DNA haplogroup background affects LHON, but not suspected LHON, in Chinese patientsProfiling the mitochondrial proteome of Leber's Hereditary Optic Neuropathy (LHON) in Thailand: down-regulation of bioenergetics and mitochondrial protein quality control pathways in fibroblasts with the 11778G>A mutationAdeno-associated virus-mediated gene delivery of the human ND4 complex I subunit in rabbit eyes.Leber's Hereditary Optic Neuropathy-Gene Therapy: From Benchtop to Bedside.Maternal transmission of Alzheimer's disease: prodromal metabolic phenotype and the search for genes.Long-term evaluation of Leber's hereditary optic neuropathy-like symptoms in rotenone administered rats.LHON: Mitochondrial Mutations and More.A method for mutagenesis of mouse mtDNA and a resource of mouse mtDNA mutations for modeling human pathological conditions.Mitochondrial gene therapy improves respiration, biogenesis, and transcription in G11778A Leber's hereditary optic neuropathy and T8993G Leigh's syndrome cells.Leber's hereditary optic neuropathy is associated with the T3866C mutation in mitochondrial ND1 gene in three Han Chinese Families.Multiplex MALDI-TOF MS detection of mitochondrial variants in Brazilian patients with hereditary optic neuropathyClinical characterization and mitochondrial DNA sequence variations in Leber hereditary optic neuropathy.Complete mitochondrial DNA genome sequence variation of Chinese families with mutation m.3635G>A and Leber hereditary optic neuropathy.Optimized allotopic expression of the human mitochondrial ND4 prevents blindness in a rat model of mitochondrial dysfunction.Mitochondrial DNA haplogroups M7b1'2 and M8a affect clinical expression of leber hereditary optic neuropathy in Chinese families with the m.11778G-->a mutation.Mitochondrial DNA variant interactions modify breast cancer risk.Pan-American mDNA haplogroups in Chilean patients with Leber's hereditary optic neuropathy.Central retinal vein occlusion as the initial manifestation of LHON / MELAS overlap syndrome with mitochondrial DNA G13513A mutation--case report and literature review.Sex disparities in neuro-ophthalmologic disorders.Mitochondrial optic neuropathy: In vivo model of neurodegeneration and neuroprotective strategies.Leber Hereditary Optic Neuropathy: Bringing the Lab to the Clinic.The exome sequencing identified the mutation in YARS2 encoding the mitochondrial tyrosyl-tRNA synthetase as a nuclear modifier for the phenotypic manifestation of Leber's hereditary optic neuropathy-associated mitochondrial DNA mutation.Leber Hereditary Optic Neuropathy: A Mitochondrial Disease Unique in Many Ways.Intravitreal delivery of AAV-NDI1 provides functional benefit in a murine model of Leber hereditary optic neuropathy.Leber Hereditary Optic Neuropathy with Interval of Visual Loss Greater Than 12 MonthsFifteen novel mutations in the mitochondrial NADH dehydrogenase subunit 1, 2, 3, 4, 4L, 5 and 6 genes from Iranian patients with Leber's hereditary optic neuropathy (LHON).Mitochondrial gene replacement in human pluripotent stem cell-derived neural progenitors.Leber's hereditary optic neuropathy masquerading as optic neuritis with spontaneous visual recovery.Oxidative stress in Chinese patients with Leber's hereditary optic neuropathy.Clinical and electrophysiology findings in Slovene patients with Leber hereditary optic neuropathy.Leber hereditary optic neuropathy due to a new ND1 mutation.Mitochondrial haplotypes may modulate the phenotypic manifestation of the LHON-associated ND1 G3460A mutation in Chinese families.Progress in Gene Therapy to Prevent Retinal Ganglion Cell Loss in Glaucoma and Leber's Hereditary Optic Neuropathy.Lebersche Optikusneuropathie
P2860
Q28395906-4566D07E-D126-4CA5-B3A0-EC4410404BB8Q30436008-5940FBA9-D890-48BB-B85D-6FB293B5C70BQ33404129-4EE29B5E-A234-4593-BC19-571ACB1DA3DAQ33484390-0916B813-715D-4C99-B569-8FCF5876C1E4Q33728325-E068818B-2C6C-43CE-95A2-34C1793EA12FQ33821139-1C452843-EE55-44EB-9D91-0EB18F6101B8Q34081807-DCFC0B15-181F-4D02-9BFD-5B784D7D04B8Q34172317-C6476330-C316-4A6A-B785-CD938604C07FQ34275931-2E0AE741-AA76-44A3-8749-58EE71D4D0A0Q34495453-E93C723D-E39F-4927-9796-B8387F8C3614Q34552263-AA069417-4889-494F-B461-422363A9EA07Q34970747-782DD7C4-7E05-4DF3-870F-C4C826144346Q35084727-F864DCE1-0002-4F22-9D46-F1F4FBF7460AQ35786077-65B7948A-4CBD-428F-BFEF-83EE0E6D90ACQ36084462-23BE443D-9951-4272-BBE2-C8ADEE009E6FQ36089268-56D015D2-3FF9-45B6-B152-7823357144C8Q36119384-8722F8B5-0FD7-4D6F-812C-B6DFFC00C09AQ36408711-EAD905FB-FBA8-40BA-AD6E-0D3D1270845FQ36511591-9E105763-F43E-4889-BE35-97A0BA24C237Q36915431-64E0C48C-07DE-438E-B942-311A778C650FQ37156232-CAA5587C-2274-4173-8F8F-18647C707BB2Q37399988-E7C349DA-D077-49A6-82B4-2C239D5664CFQ37656235-F84CC1B7-31AD-4EAD-812F-D5B5588122F0Q37822728-3F232BD0-157E-4096-906B-E7A6B03438F1Q38218704-21B7F42B-EA4F-47F3-AD44-1902CAAEF66DQ38766331-F436CD4F-7E19-450B-B60F-9985749A79BBQ38766836-63420E38-BB87-4851-B8BB-7CCB5A5984C9Q38813517-73790FDB-6CCF-4FE3-B743-4E448E088CB7Q40511873-F592D67E-B295-41BC-9FF2-C0960B02ABA4Q41821755-F16A4C6D-B2CA-4A75-A1E4-61578BC6DA6FQ42363529-B638C56A-F694-43C9-A07A-DE1712074E38Q43826118-66D124D6-B3B5-42C5-BA9D-E40D44CB57F1Q44969189-42A283B4-6BA7-44E3-BDD4-CF28C0BC70C2Q45323348-E397670B-997F-4B92-B3B6-08D194D670CCQ46556291-FD906CF7-F4E6-4868-A6B3-D9AC2D9F3A71Q51054298-54EC012E-1D15-4F96-9A04-584388B75161Q51160954-CEB77D36-9BF9-4FF0-BB27-002E739A38CFQ53072695-745CA8BA-B3E0-4577-B0C0-125FFC8B866BQ55039934-059B7F6A-CFCC-46C7-83F9-98215C9C13FCQ56959652-2337DBC3-A673-4A09-8FC9-475180DD88C7
P2860
Leber's hereditary optic neuropathy: a multifactorial disease.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Leber's hereditary optic neuropathy: a multifactorial disease.
@ast
Leber's hereditary optic neuropathy: a multifactorial disease.
@en
type
label
Leber's hereditary optic neuropathy: a multifactorial disease.
@ast
Leber's hereditary optic neuropathy: a multifactorial disease.
@en
prefLabel
Leber's hereditary optic neuropathy: a multifactorial disease.
@ast
Leber's hereditary optic neuropathy: a multifactorial disease.
@en
P1476
Leber's hereditary optic neuropathy: a multifactorial disease
@en
P2093
An-Guor Wang
May-Yung Yen
P304
P356
10.1016/J.PRETEYERES.2006.05.002
P50
P577
2006-07-07T00:00:00Z