Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response.
about
Krüppel-like factor 17, a novel tumor suppressor: its low expression is involved in cancer metastasisProgression of cutaneous melanoma: implications for treatmentIn vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells.Cancer Cell Colonisation in the Bone MicroenvironmentThe role of p21 in regulating mammalian regenerationTGFbeta in CancerKLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancerE Proteins and ID Proteins: Helix-Loop-Helix Partners in Development and Diseasep21 in cancer: intricate networks and multiple activitiesLimited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression.Redefining the expression and function of the inhibitor of differentiation 1 in mammary gland developmentTGF-β1 induces senescence of bone marrow mesenchymal stem cells via increase of mitochondrial ROS productionDefining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activationNew insights into the role of ID proteins in breast cancer metastasis: a MET affairRas oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia.Analysis of gene expression in PTHrP-/- mammary buds supports a role for BMP signaling and MMP2 in the initiation of ductal morphogenesis.Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis.3'LIFE: a functional assay to detect miRNA targets in high-throughputMolecular basis of metastasis.p14ARF post-transcriptional regulation of nuclear cyclin D1 in MCF-7 breast cancer cells: discrimination between a good and bad prognosis?Targeting multiple cannabinoid anti-tumour pathways with a resorcinol derivative leads to inhibition of advanced stages of breast cancer.miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma.Interleukin-27 signaling promotes immunity against endogenously arising murine tumors.The Antitumor Activity of Plant-Derived Non-Psychoactive Cannabinoids.Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways.A p53/ARF-dependent anticancer barrier activates senescence and blocks tumorigenesis without impacting apoptosisID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities.Loss of TGF-β signaling and PTEN promotes head and neck squamous cell carcinoma through cellular senescence evasion and cancer-related inflammation.Inhibition of BMP and of TGFβ receptors downregulates expression of XIAP and TAK1 leading to lung cancer cell death.Overexpression of Id1 in transgenic mice promotes mammary basal stem cell activity and breast tumorigenesisSenescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1.Id1 overexpression is independent of repression and epigenetic silencing of tumor suppressor genes in melanomaCyclooxygenase-2-derived prostaglandin E2 stimulates Id-1 transcription.Activation of the aryl hydrocarbon receptor by TCDD inhibits senescence: a tumor promoting event?DJ-1 upregulates breast cancer cell invasion by repressing KLF17 expression.Regulation of tissue- and stimulus-specific cell fate decisions by p53 in vivo.Oncogene-induced senescence and its role in tumor suppression.Clinical significance of cell cycle inhibitors in hepatocellular carcinoma.Tumor metastasis: moving new biological insights into the clinic.Regulation of cellular iron metabolism and its implications in lung cancer progression.
P2860
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P2860
Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Id1 cooperates with oncogenic ...... cellular senescence response.
@ast
Id1 cooperates with oncogenic ...... cellular senescence response.
@en
type
label
Id1 cooperates with oncogenic ...... cellular senescence response.
@ast
Id1 cooperates with oncogenic ...... cellular senescence response.
@en
prefLabel
Id1 cooperates with oncogenic ...... cellular senescence response.
@ast
Id1 cooperates with oncogenic ...... cellular senescence response.
@en
P2093
P2860
P356
P1476
Id1 cooperates with oncogenic ...... cellular senescence response.
@en
P2093
Alexander Swarbrick
J Michael Bishop
Thaddeus Allen
P2860
P304
P356
10.1073/PNAS.0801505105
P407
P577
2008-03-31T00:00:00Z