Components of the nuclear signaling cascade that regulate collagenase gene expression in response to integrin-derived signals.
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Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinasesType VIII collagen stimulates smooth muscle cell migration and matrix metalloproteinase synthesis after arterial injuryIntegrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activityJAB1/CSN5 and the COP9 signalosome. A complex situationRegulation of a multigenic invasion programme by the transcription factor, AP-1: re-expression of a down-regulated gene, TSC-36, inhibits invasion.Integrins as "functional hubs" in the regulation of pathological angiogenesisRole of metalloproteinases in liver fibrosis.Proteolytic events of wound-healing--coordinated interactions among matrix metalloproteinases (MMPs), integrins, and extracellular matrix molecules.Granzyme B mediates both direct and indirect cleavage of extracellular matrix in skin after chronic low-dose ultraviolet light irradiation.Increased plasminogen activator inhibitor-1 in keloid fibroblasts may account for their elevated collagen accumulation in fibrin gel culturesDifferential expression of matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase genes in the mouse central nervous system in normal and inflammatory states.Biomechanical regulation of human monocyte/macrophage molecular functionTiron Inhibits UVB-Induced AP-1 Binding Sites Transcriptional Activation on MMP-1 and MMP-3 Promoters by MAPK Signaling Pathway in Human Dermal Fibroblasts.The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells.Platinum-sensitive recurrence in ovarian cancer: the role of tumor microenvironment.Induction of MMP-1 (collagenase-1) by relaxin in fibrocartilaginous cells requires both the AP-1 and PEA-3 promoter sitesPhagocytosis mediated by Yersinia invasin induces collagenase-1 expression in rabbit synovial fibroblasts through a proinflammatory cascade.Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: evidence for involvement of AP-1 and PEA3.Regulation of human interstitial collagenase (matrix metalloproteinase-1) promoter activity by fibroblast growth factor.Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences.Integrin-mediated adhesion of endothelial cells induces JAK2 and STAT5A activation: role in the control of c-fos gene expression.Increased expression levels of integrin alphavbeta5 on scleroderma fibroblasts.Analytic study of three-dimensional single cell migration with and without proteolytic enzymesRetinoic acid inhibits induction of c-Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen-activated protein kinase pathways in human skin in vivo.Attenuation of plasminogen activator inhibitor type-1 promoter activity in serum-stimulated renal epithelial cells by a distal 5' flanking region.Tumor-derived EMMPRIN (extracellular matrix metalloproteinase inducer) stimulates collagenase transcription through MAPK p38.Alterations in human glomerular epithelial cells interacting with nonenzymatically glycosylated matrix.Role of plasminogen activator inhibitor in the reciprocal regulation of bovine aortic endothelial and smooth muscle cell migration by TGF-beta 1.CCAAT-enhancer-binding proteins (C/EBP) regulate the tissue specific activity of the CD11c integrin gene promoter through functional interactions with Sp1 proteins.The role of proteases in fibronectin matrix remodeling in thyroid epithelial cell monolayer cultures.Immunohistochemical analysis of TIMP-2 and collagen types I and IV in experimental spinal cord ischemia-reperfusion injury in rats.Integrin alpha(v)beta(3)/vitronectin interaction affects expression of the urokinase system in human ovarian cancer cells.Analysis of immunohistochemical label of Fos protein in the suprachiasmatic nucleus: comparison of different methods of quantification.Glucose-induced changes in integrins and matrix-related functions in cultured human glomerular epithelial cells.AlphaV integrins play an important role in myofibroblast differentiation.Synergistic transcriptional activation of the tissue inhibitor of metalloproteinases-1 promoter via functional interaction of AP-1 and Ets-1 transcription factors.Disruption of fibronectin binding to the alpha 5 beta 1 integrin stimulates the expression of cyclin-dependent kinases and DNA synthesis through activation of extracellular signal-regulated kinase.
P2860
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P2860
Components of the nuclear signaling cascade that regulate collagenase gene expression in response to integrin-derived signals.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Components of the nuclear sign ...... e to integrin-derived signals.
@ast
Components of the nuclear sign ...... e to integrin-derived signals.
@en
type
label
Components of the nuclear sign ...... e to integrin-derived signals.
@ast
Components of the nuclear sign ...... e to integrin-derived signals.
@en
prefLabel
Components of the nuclear sign ...... e to integrin-derived signals.
@ast
Components of the nuclear sign ...... e to integrin-derived signals.
@en
P2093
P2860
P356
P1476
Components of the nuclear sign ...... e to integrin-derived signals.
@en
P2093
P2860
P304
P356
10.1083/JCB.129.6.1707
P407
P577
1995-06-01T00:00:00Z