Methylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models - Wikidata - awgldk - TriplyDB

Methylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models

Methylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models

http://www.wikidata.org/entity/Q36538885

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Successful therapies for Alzheimer's disease: why so many in animal models and none in humans?Attenuation of noise-induced hearing loss using methylene blue.Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau.A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript.Proteasome-mediated proteolysis of the polyglutamine-expanded androgen receptor is a late event in spinal and bulbar muscular atrophy (SBMA) pathogenesis.Alleviating neurodegeneration in Drosophila models of PolyQ diseases.TRIM32-Cytoplasmic-Body Formation Is an ATP-Consuming Process Stimulated by HSP70 in Cells.Reversing the Warburg effect as a treatment for glioblastoma.Selective reduction of striatal mature BDNF without induction of proBDNF in the zQ175 mouse model of Huntington's disease Alternative mitochondrial electron transfer for the treatment of neurodegenerative diseases and cancers: Methylene blue connects the dots.Aggregation formation in the polyglutamine diseases: protection at a cost?TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington's disease SUMO-2 and PIAS1 modulate insoluble mutant huntingtin protein accumulation.Experimental models for identifying modifiers of polyglutamine-induced aggregation and neurodegeneration.Prions Ex Vivo: What Cell Culture Models Tell Us about Infectious Proteins.Potential therapeutic targets in polyglutamine-mediated diseases.Studying polyglutamine diseases in Drosophila.Shedding Light on Alzheimer's β-Amyloidosis: Photosensitized Methylene Blue Inhibits Self-Assembly of β-Amyloid Peptides and Disintegrates Their Aggregates.Tau-directed approaches for the treatment of Alzheimer's disease: focus on leuco-methylthioninium.Nanoparticulate strategies for the treatment of polyglutamine diseases by halting the protein aggregation process.Methylene Blue Partially Rescues Heart Defects in a Drosophila Model of Huntington's Disease.Methylene Blue Attenuates iNOS Induction Through Suppression of Transcriptional Factor Binding Amid iNOS mRNA Transcription.RTP801 Is Involved in Mutant Huntingtin-Induced Cell Death.Tau aggregation inhibitors: the future of Alzheimer's pharmacotherapy?Autophagy-mediated clearance of ubiquitinated mutant huntingtin by graphene oxide.Fractionation for Resolution of Soluble and Insoluble Huntingtin Species.Pharmacological Agents Targeting the Cellular Prion Protein.

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Methylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models

http://www.wikidata.org/entity/Q36538885

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Methylene blue modulates hunti ...... in Huntington's disease models

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Methylene blue modulates hunti ...... in Huntington's disease models

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Methylene blue modulates hunti ...... in Huntington's disease models

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Methylene blue modulates hunti ...... in Huntington's disease models

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Methylene blue modulates hunti ...... in Huntington's disease models

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JNEUROSCI.0895-12.2012

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Journal of Neuroscience

P1476

Methylene blue modulates hunti ...... in Huntington's disease models

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P2093

Alice Lau

http://www.w3.org/2001/XMLSchema#string

Andrew Tran

http://www.w3.org/2001/XMLSchema#string

Charles Glabe

http://www.w3.org/2001/XMLSchema#string

Emily Mitchell Sontag

http://www.w3.org/2001/XMLSchema#string

Gregor P Lotz

http://www.w3.org/2001/XMLSchema#string

Guocheng Yang

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J Lawrence Marsh

http://www.w3.org/2001/XMLSchema#string

Leslie M Thompson

http://www.w3.org/2001/XMLSchema#string

Mihaela Necula

http://www.w3.org/2001/XMLSchema#string

Namita Agrawal

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P2860

Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation

Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines

Methylene blue reduces aβ levels and rescues early cognitive deficit by increasing proteasome activity

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

Methylene blue in the treatment and prevention of ifosfamide-induced encephalopathy: report of 12 cases and a review of the literature

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

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11109-11119

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scholarly article

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10.1523/JNEUROSCI.0895-12.2012

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32

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2012-08-01T00:00:00Z

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230638906

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22875942

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Huntington disease

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3546821

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