DNA synthesis and DNA polymerase activity of herpes simplex virus type 1 temperature-sensitive mutants.
about
Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanineEfficacies of antiherpesvirus nucleosides against two strains of herpes simplex virus type 1 in Vero and human embryo lung fibroblast cellsInhibition of cellular and virus-associated nucleotide polymerases by, and anti-herpes simplex virus activity of, streptovaricin derivatives2'-fluoro-5-iodo-aracytosine, a potent and selective anti-herpesvirus agentIdentification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition.Ultrastructural characterization of an early, nonstructural polypeptide of herpes simplex virus type 1.Molecular genetics of herpes simplex virus. VII. Characterization of a temperature-sensitive mutant produced by in vitro mutagenesis and defective in DNA synthesis and accumulation of gamma polypeptidesMethod for induction of mutations in physically defined regions of the herpes simplex virus genome.On the mechanism of selective inhibition of herpesvirus replication by (E)-5-(2-bromovinyl)-2'-deoxyuridine.Enzymatic activities of overexpressed herpes simplex virus DNA polymerase purified from recombinant baculovirus-infected insect cells.Resistance of herpes simplex virus to 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine: physical mapping of drug synergism within the viral DNA polymerase locusResistance of herpes simplex virus to acycloguanosine: role of viral thymidine kinase and DNA polymerase loci.Molecular genetics of herpes simplex virus. II. Mapping of the major viral glycoproteins and of the genetic loci specifying the social behavior of infected cellsSynthesis of viral and host DNA in isolated chromatin from herpes simplex virus-infected HeLa cells.Distinguishing cytomegalovirus, mycoplasma, and cellular DNA polymerases.The extreme C terminus of herpes simplex virus DNA polymerase is crucial for functional interaction with processivity factor UL42 and for viral replication.Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficientHerpes simplex virus type 1 gene products required for DNA replication: identification and overexpression.Herpes simplex virus type 1 DNA synthesis requires the product of the UL8 gene: isolation and characterization of an ICP6::lacZ insertion mutation.Isolation and characterization of herpes simplex virus mutants containing engineered mutations at the DNA polymerase locus.Isolation and characterization of herpes simplex virus type 1 host range mutants defective in viral DNA synthesis.Herpes simplex virus type 1-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis: isolation and characterization of an ICP6 lacZ insertion mutant.Expression of herpes simplex virus type 1 DNA polymerase gene by in vitro translation and effects of gene deletions on activityA temperature-sensitive mutation in a herpes simplex virus type 1 gene required for viral DNA synthesis maps to coordinates 0.609 through 0.614 in ULAn ICP6::lacZ insertional mutagen is used to demonstrate that the UL52 gene of herpes simplex virus type 1 is required for virus growth and DNA synthesisDeletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture.Isolation and characterization of phosphonoacetic acid-resistant mutants of human cytomegalovirus.Functional expression of a cloned herpes simplex virus type 1 DNA polymerase geneTemperature-sensitive mutants in herpes simplex virus type 1 ICP4 permissive for early gene expression.Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locusHerpes simplex virus type 1 ICP27 is an essential regulatory protein.Physical mapping of two herpes simplex virus type 1 host shutoff loci: rescue of each ts mutation occurs with two unique cloned regions of the viral genome.Mutations in the major DNA-binding protein gene of herpes simplex virus type 1 result in increased levels of viral gene expressionGenetic and phenotypic analysis of herpes simplex virus type 1 mutants conditionally resistant to immune cytolysisFine mapping and molecular cloning of mutations in the herpes simplex virus DNA polymerase locusTranscriptional and genetic analyses of the herpes simplex virus type 1 genome: coordinates 0.29 to 0.45Characterization of the major mRNAs transcribed from the genes for glycoprotein B and DNA-binding protein ICP8 of herpes simplex virus type 1.Isolation and preliminary characterization of a phosphonoacetic acid-resistant and temperature-sensitive mutant of herpes simplex virus type 1Genetic analysis of temperature-sensitive mutants which define the genes for the major herpes simplex virus type 2 DNA-binding protein and a new late functionGenetic analysis of temperature-sensitive mutants which define the gene for the major herpes simplex virus type 1 DNA-binding protein.
P2860
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P2860
DNA synthesis and DNA polymerase activity of herpes simplex virus type 1 temperature-sensitive mutants.
description
1975 nî lūn-bûn
@nan
1975年の論文
@ja
1975年論文
@yue
1975年論文
@zh-hant
1975年論文
@zh-hk
1975年論文
@zh-mo
1975年論文
@zh-tw
1975年论文
@wuu
1975年论文
@zh
1975年论文
@zh-cn
name
DNA synthesis and DNA polymera ...... temperature-sensitive mutants.
@ast
DNA synthesis and DNA polymera ...... temperature-sensitive mutants.
@en
type
label
DNA synthesis and DNA polymera ...... temperature-sensitive mutants.
@ast
DNA synthesis and DNA polymera ...... temperature-sensitive mutants.
@en
prefLabel
DNA synthesis and DNA polymera ...... temperature-sensitive mutants.
@ast
DNA synthesis and DNA polymera ...... temperature-sensitive mutants.
@en
P2093
P2860
P1433
P1476
DNA synthesis and DNA polymera ...... temperature-sensitive mutants.
@en
P2093
P2860
P304
P407
P577
1975-09-01T00:00:00Z