The role of glutathione-dependent enzymes in drug resistance.
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Overexpression of the regulatory subunit of gamma-glutamylcysteine synthetase in HeLa cells increases gamma-glutamylcysteine synthetase activity and confers drug resistanceGlutathione S-transferase P1 (GSTP1) directly influences platinum drug chemosensitivity in ovarian tumour cell lines.Effect of Vitamin E on Glutathione-Dependent EnzymesGenomic cloning and characterization of the rat glutathione S-transferase-A3-subunit geneCharacterization of human soft-tissue sarcoma xenografts for use in secondary drug screeningModeling the chemoprotective functions of glutathione S-transferases in cultured cell lines by heterologous expression.Pregnant rat uterus expresses high levels of the type 3 iodothyronine deiodinaseEvaluation of differential gene expression in fluconazole-susceptible and -resistant isolates of Candida albicans by cDNA microarray analysis.In vivo induction of phase II detoxifying enzymes, glutathione transferase and quinone reductase by citrus triterpenoids.Genome-wide expression profile analysis reveals coordinately regulated genes associated with stepwise acquisition of azole resistance in Candida albicans clinical isolates.Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery.Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi.Increased skin tumorigenesis in mice lacking pi class glutathione S-transferasesP-glycoprotein and glutathione S-transferase pi in childhood acute lymphoblastic leukaemiaGenome-wide expression and location analyses of the Candida albicans Tac1p regulon.Dual roles of Nrf2 in cancer.Ribozyme-mediated cleavage of the MDR-1 transcript restores chemosensitivity in previously resistant cancer cells.Knockout and transgenic mice in glutathione transferase research.Stimuli-responsive cross-linked micelles for on-demand drug delivery against cancers.Endothelial cells do not express GSTA1: potential relevance to busulfan-mediated endothelial damage during haematopoietic stem cell transplantation.Ethacrynic acid and its glutathione conjugate as inhibitors of glutathione S-transferases.Use of transgenic animals in understanding molecular mechanisms of toxicity.Increased levels of alpha-class and pi-class glutathione S-transferases in cell lines resistant to 1-chloro-2,4-dinitrobenzene.Proteomic analysis of Mrr1p- and Tac1p-associated differential protein expression in azole-resistant clinical isolates of Candida albicans.Isolation and characterization of two mouse Pi-class glutathione S-transferase genes.Glutathione-S-transferase activity in malarial parasites.Activation of mouse Pi-class glutathione S-transferase gene by Nrf2(NF-E2-related factor 2) and androgen.Co-variation of glutathione transferase expression and cytostatic drug resistance in HeLa cells: establishment of class Mu glutathione transferase M3-3 as the dominating isoenzyme.Cytochrome P450 expression in oesophageal cancer.Xenobiotic metabolising enzyme expression in colonic neoplasia.Susceptibility of cord blood antioxidant enzymes glutathione reductase, glutathione peroxidase and glutathione S-transferase to different antibiotics: in vitro approach.Glutathione is a target in tellurite toxicity and is protected by tellurite resistance determinants in Escherichia coli.Coordinated action of glutathione S-transferases (GSTs) and multidrug resistance protein 1 (MRP1) in antineoplastic drug detoxification. Mechanism of GST A1-1- and MRP1-associated resistance to chlorambucil in MCF7 breast carcinoma cells.Noninvasive detection of enzyme activity in tumor models of human ovarian cancer using catalyCEST MRI.Role of multidrug-resistance protein 2 in glutathione S-transferase P1-1-mediated resistance to 4-nitroquinoline 1-oxide toxicities in HepG2 cells.Qualitatively different mechanisms of resistance to doxorubicin, both involving altered glutathione pools, in two myeloid cell lines in vitro.High field proton NMR investigations of the metabolic profiles of multidrug-sensitive and -resistant leukaemic cell lines: evidence for diminished taurine levels in multidrug-resistant cells.
P2860
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P2860
The role of glutathione-dependent enzymes in drug resistance.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
The role of glutathione-dependent enzymes in drug resistance.
@ast
The role of glutathione-dependent enzymes in drug resistance.
@en
type
label
The role of glutathione-dependent enzymes in drug resistance.
@ast
The role of glutathione-dependent enzymes in drug resistance.
@en
prefLabel
The role of glutathione-dependent enzymes in drug resistance.
@ast
The role of glutathione-dependent enzymes in drug resistance.
@en
P1476
The role of glutathione-dependent enzymes in drug resistance.
@en
P2093
P304
P356
10.1016/0163-7258(91)90044-M
P577
1991-01-01T00:00:00Z