Osteoblast lineage-specific effects of notch activation in the skeleton
about
Notch signaling in osteocytes differentially regulates cancellous and cortical bone remodelingOsteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone.Mutations in NOTCH2 in patients with Hajdu-Cheney syndrome.Connective tissue growth factor is a target of notch signaling in cells of the osteoblastic lineage.Maintenance of Bone Homeostasis by DLL1-Mediated Notch SignalingIntermittent activation of notch signaling promotes bone formation.Nemo-like kinase regulates postnatal skeletal homeostasis.Downregulation of Notch modulators, tetraspanin 5 and 10, inhibits osteoclastogenesis in vitro.Notch activation as a driver of osteogenic sarcoma.Vitamin D: direct effects of vitamin D metabolites on bone: lessons from genetically modified mice.Hajdu-Cheney syndrome: a review.mTORC1 Prevents Preosteoblast Differentiation through the Notch Signaling Pathway.LRP6 in mesenchymal stem cells is required for bone formation during bone growth and bone remodeling.Notch signaling in skeletal health and disease.Osteocytes and Skeletal PathophysiologyCanonical Notch activation in osteocytes causes osteopetrosis.Hajdu Cheney Mouse Mutants Exhibit Osteopenia, Increased Osteoclastogenesis, and Bone Resorption.MicroRNAs and Bone Regeneration.The Dmp1-SOST Transgene Interacts With and Downregulates the Dmp1-Cre Transgene and the Rosa(Notch) AlleleNotch Signaling and the Skeleton.Systemic inhibition of canonical Notch signaling results in sustained callus inflammation and alters multiple phases of fracture healing.Hairy and Enhancer of Split-related with YRPW motif (HEY)2 regulates bone remodeling in miceDisruption of LRP6 in osteoblasts blunts the bone anabolic activity of PTH.Interleukin 6 mediates selected effects of Notch in chondrocytes.Effects of age on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in humansEffects of estrogen on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in postmenopausal women.Sex and genetic factors determine osteoblastic differentiation potential of murine bone marrow stromal cells.Notch signaling in skeletal stem cells.Notch1 and Notch2 expression in osteoblast precursors regulates femoral microarchitectureNotch signaling and bone remodeling.MicroRNAs regulate bone metabolism.The role of notch signaling in bone marrow niche.MicroRNAs in bone development and their diagnostic and therapeutic potentials in osteoporosis.TNF and Bone Remodeling.Analysis of αSMA-labeled progenitor cell commitment identifies notch signaling as an important pathway in fracture healingJagged1 expression by osteoblast-lineage cells regulates trabecular bone mass and periosteal expansion in mice.Osx-Cre targets multiple cell types besides osteoblast lineage in postnatal mice.Ubiquitin E3 Ligase LNX2 is Critical for Osteoclastogenesis In Vitro by Regulating M-CSF/RANKL Signaling and Notch2.Parathyroid hormone inhibits Notch signaling in osteoblasts and osteocytes.Hajdu Cheney Syndrome; report of a novel NOTCH2 mutation and treatment with denosumab
P2860
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P2860
Osteoblast lineage-specific effects of notch activation in the skeleton
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Osteoblast lineage-specific effects of notch activation in the skeleton
@ast
Osteoblast lineage-specific effects of notch activation in the skeleton
@en
type
label
Osteoblast lineage-specific effects of notch activation in the skeleton
@ast
Osteoblast lineage-specific effects of notch activation in the skeleton
@en
prefLabel
Osteoblast lineage-specific effects of notch activation in the skeleton
@ast
Osteoblast lineage-specific effects of notch activation in the skeleton
@en
P2093
P2860
P356
P1433
P1476
Osteoblast lineage-specific effects of notch activation in the skeleton
@en
P2093
Ernesto Canalis
Jian Q Feng
Kristen Parker
Stefano Zanotti
P2860
P304
P356
10.1210/EN.2012-1732
P407
P577
2012-12-28T00:00:00Z