Involvement of distinct arrestin-1 elements in binding to different functional forms of rhodopsin
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Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laserStructure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptideCrystal structure of pre-activated arrestin p44Visualization of arrestin recruitment by a G-protein-coupled receptorNMR as a tool to investigate the structure, dynamics and function of membrane proteins.The quiet renaissance of protein nuclear magnetic resonance.Rhodopsin TM6 can interact with two separate and distinct sites on arrestin: evidence for structural plasticity and multiple docking modes in arrestin-rhodopsin bindingProteomic analysis of human vitreous humor.Identification of receptor binding-induced conformational changes in non-visual arrestins.Conformational selection and equilibrium governs the ability of retinals to bind opsin.C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptorPhospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR.Critical role of the central 139-loop in stability and binding selectivity of arrestin-1.Functional map of arrestin binding to phosphorylated opsin, with and without agonist.Effect of Rhodopsin Phosphorylation on Dark Adaptation in Mouse Rods.Molecular Pharmacology of δ-Opioid Receptors.Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 bindingJNK3 enzyme binding to arrestin-3 differentially affects the recruitment of upstream mitogen-activated protein (MAP) kinase kinasesFunctional map of arrestin-1 at single amino acid resolutionRole of β-arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking.Structural determinants of arrestin functionsExtensive shape shifting underlies functional versatility of arrestins.Overview of different mechanisms of arrestin-mediated signaling.Peptide mini-scaffold facilitates JNK3 activation in cellsHitchhiking on the heptahelical highway: structure and function of 7TM receptor complexes.Structural evidence for the role of polar core residue Arg175 in arrestin activation.Formation and decay of the arrestin·rhodopsin complex in native disc membranes.Crystal structure of a common GPCR-binding interface for G protein and arrestin.Targeting individual GPCRs with redesigned nonvisual arrestins.Self-association of arrestin family members.Arrestin-3 binds the MAP kinase JNK3α2 via multiple sites on both domains.Rapid degeneration of rod photoreceptors expressing self-association-deficient arrestin-1 mutant.Arrestins in apoptosis.Therapeutic potential of small molecules and engineered proteins.Arrestin-dependent activation of JNK family kinasesEnhanced phosphorylation-independent arrestins and gene therapy.The rhodopsin-arrestin-1 interaction in bicelles.Differential manipulation of arrestin-3 binding to basal and agonist-activated G protein-coupled receptors.Arrestin expression in E. coli and purification.Influence of Arrestin on the Photodecay of Bovine Rhodopsin.
P2860
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P2860
Involvement of distinct arrestin-1 elements in binding to different functional forms of rhodopsin
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Involvement of distinct arrest ...... functional forms of rhodopsin
@ast
Involvement of distinct arrest ...... functional forms of rhodopsin
@en
type
label
Involvement of distinct arrest ...... functional forms of rhodopsin
@ast
Involvement of distinct arrest ...... functional forms of rhodopsin
@en
prefLabel
Involvement of distinct arrest ...... functional forms of rhodopsin
@ast
Involvement of distinct arrest ...... functional forms of rhodopsin
@en
P2093
P2860
P356
P1476
Involvement of distinct arrest ...... functional forms of rhodopsin
@en
P2093
Charles R Sanders
Min-Kyu Cho
Qiuyan Chen
Sergey A Vishnivetskiy
Tiandi Zhuang
Tina M Iverson
Vsevolod V Gurevich
P2860
P304
P356
10.1073/PNAS.1215176110
P407
P577
2012-12-31T00:00:00Z