Loss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression

about

p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway.The non-canonical functions of p27(Kip1) in normal and tumor biology.Acinar cell plasticity and development of pancreatic ductal adenocarcinoma.

P2860

Q33554593-8A763963-55D7-4A36-99FC-5A20B1346DAD Q36956895-23312E67-A513-4175-AD79-3D675FD0B514 Q38922230-70D163E4-D6C3-451A-AD87-F797C6DAD781

P2860

Loss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression

Item

http://www.wikidata.org/entity/Q36546501

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

Loss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression

@ast

Loss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression

@en

type

Item

label

Loss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression

@ast

Loss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression

@en

prefLabel

Loss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression

@ast

Loss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression

@en

P1476

Loss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression

@en

P2093

Caroline Callot

http://www.w3.org/2001/XMLSchema#string

Nicolas Duquesnes

http://www.w3.org/2001/XMLSchema#string

Oriol Bachs

http://www.w3.org/2001/XMLSchema#string

P2860

Hallmarks of Cancer: The Next Generation

Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels

RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.

Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans

CDK inhibitors: positive and negative regulators of G1-phase progression

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

Supramaximal cholecystokinin displaces Munc18c from the pancreatic acinar basal surface, redirecting apical exocytosis to the basal membrane

SOX9 is required for maintenance of the pancreatic progenitor cell pool

EGF receptor is required for KRAS-induced pancreatic tumorigenesis

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

P304

35880-35892

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.18632/ONCOTARGET.5770

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Julie Guillermet-Guibert

P577

2015-09-21T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

282344932

http://www.w3.org/2001/XMLSchema#string

P698

26416424

http://www.w3.org/2001/XMLSchema#string

P921

Aizkuņģa dziedzeris

P932

4742148

http://www.w3.org/2001/XMLSchema#string

Loss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression

about

P2860

P2860

Loss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P921

P932