Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin
about
Matriptase zymogen supports epithelial development, homeostasis and regenerationSelective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2Delineation of proteolytic and non-proteolytic functions of the membrane-anchored serine protease prostasin.Functional analysis of corin protein domains required for PCSK6-mediated activation.Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin.Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis.Loss of HAI-2 in mice with decreased prostasin activity leads to an early-onset intestinal failure resembling congenital tufting enteropathy.
P2860
Q33749952-769EE19C-7DC2-435E-8EA9-FB48F574D8C2Q36261355-B5387D52-19D5-4E60-A011-A6D0CC5B0BC5Q39626361-20114843-18D9-4398-AD8F-FB1FA906128BQ47359170-12835FAE-992E-4EDC-B7EE-05C08C311322Q50041747-5A2E0FC9-13A7-4A41-9980-534E93F20B5AQ51009956-27364CF7-B700-4AB4-B7D5-84D99B6E70B8Q54948226-019FEB71-3434-428A-A595-7133FBD4F08C
P2860
Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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2015年论文
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2015年论文
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name
Distinct Developmental Functio ...... ymogen and Activated Prostasin
@ast
Distinct Developmental Functio ...... ymogen and Activated Prostasin
@en
type
label
Distinct Developmental Functio ...... ymogen and Activated Prostasin
@ast
Distinct Developmental Functio ...... ymogen and Activated Prostasin
@en
prefLabel
Distinct Developmental Functio ...... ymogen and Activated Prostasin
@ast
Distinct Developmental Functio ...... ymogen and Activated Prostasin
@en
P2860
P356
P1476
Distinct Developmental Functio ...... ymogen and Activated Prostasin
@en
P2093
Daniel H Madsen
Stine Friis
P2860
P304
P356
10.1074/JBC.C115.706721
P407
P577
2015-12-30T00:00:00Z