Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.
about
Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2Defining the function of xeroderma pigmentosum group F protein in psoralen interstrand cross-link-mediated DNA repair and mutagenesisTherapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificitiesTriplex-induced recombination and repair in the pyrimidine motif.Developing a programmed restriction endonuclease for highly specific DNA cleavageTriplex targeted genomic crosslinks enter separable deletion and base substitution pathwaysThe hidden side of unstable DNA repeats: Mutagenesis at a distanceTargeted inhibition of transcription elongation in cells mediated by triplex-forming oligonucleotidesMutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions and frameshiftsDifferent mutator phenotypes in Mlh1- versus Pms2-deficient miceTriplex-induced recombination in human cell-free extracts. Dependence on XPA and HsRad51.Detection and determination of oligonucleotide triplex formation-mediated transcription-coupled DNA repair in HeLa nuclear extracts.Targeted correction of an episomal gene in mammalian cells by a short DNA fragment tethered to a triplex-forming oligonucleotide.Triple-helix formation induces recombination in mammalian cells via a nucleotide excision repair-dependent pathway.Site-directed recombination via bifunctional PNA-DNA conjugates.Spatially localized generation of nucleotide sequence-specific DNA damageHuman XPA and RPA DNA repair proteins participate in specific recognition of triplex-induced helical distortionsImproved bioactivity of G-rich triplex-forming oligonucleotides containing modified guanine bases.Understanding oligonucleotide-mediated inhibition of gene expression in Xenopus laevis oocytes.DNA interstrand crosslink repair in mammalian cells: step by step.Blocking transcription of the human rhodopsin gene by triplex-mediated DNA photocrosslinkingSuppression of gene expression by targeted disruption of messenger RNA: available options and current strategies.DNA binding and antigene activity of a daunomycin-conjugated triplex-forming oligonucleotide targeting the P2 promoter of the human c-myc gene.Triplex-forming molecules: from concepts to applications.Effect of third strand composition on the triple helix formation: purine versus pyrimidine oligodeoxynucleotidesTargeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleasesDetection of covalent triplex within human cellsOverexpressed DNA polymerase iota regulated by JNK/c-Jun contributes to hypermutagenesis in bladder cancer.Site-specific mutagenesis by triple helix-forming oligonucleotides containing a reactive nucleoside analog.Optimization of the piggyBac transposon using mRNA and insulators: toward a more reliable gene delivery system.Unambiguous demonstration of triple-helix-directed gene modification.Effect of DNA target sequence on triplex formation by oligo-2'-deoxy- and 2'-O-methylribonucleotides.High-frequency intrachromosomal gene conversion induced by triplex-forming oligonucleotides microinjected into mouse cells.The potential for gene repair via triple helix formation.Repairing the Sickle Cell mutation. II. Effect of psoralen linker length on specificity of formation and yield of third strand-directed photoproducts with the mutant target sequence.Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells.Accessibility of nuclear DNA to triplex-forming oligonucleotides: the integrated HIV-1 provirus as a targetLocal delivery of gene-modifying triplex-forming molecules to the epidermis.Processing of targeted psoralen cross-links in Xenopus oocytes.Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA.
P2860
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P2860
Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.
@ast
Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.
@en
type
label
Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.
@ast
Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.
@en
prefLabel
Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.
@ast
Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.
@en
P2093
P2860
P356
P1476
Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.
@en
P2093
P2860
P304
P356
10.1128/MCB.15.3.1759
P407
P577
1995-03-01T00:00:00Z