The role of phosphorylation in D1 dopamine receptor desensitization: evidence for a novel mechanism of arrestin association
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Dopamine D1-D2 receptor Heteromer-mediated calcium release is desensitized by D1 receptor occupancy with or without signal activation: dual functional regulation by G protein-coupled receptor kinase 2The structural basis of arrestin-mediated regulation of G-protein-coupled receptorsFunctional selectivity of dopamine D1 receptor agonists in regulating the fate of internalized receptorsEndocytosis promotes rapid dopaminergic signalingThe elevated blood pressure of human GRK4gamma A142V transgenic mice is not associated with increased ROS productionA dopamine D2 receptor mutant capable of G protein-mediated signaling but deficient in arrestin bindingMutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neuronsNovel role of sorting nexin 5 in renal D(1) dopamine receptor trafficking and function: implications for hypertension.G protein-coupled receptor kinase-2 constitutively regulates D2 dopamine receptor expression and signaling independently of receptor phosphorylation.D1 dopamine receptor-mediated LTP at GABA synapses encodes motivation to self-administer cocaine in rats.Role of LRRK2 in the regulation of dopamine receptor traffickingC-terminal di-leucine motif of dopamine D₁ receptor plays an important role in its plasma membrane trafficking.Dopamine D(3) receptors are down-regulated following heterologous endocytosis by a specific interaction with G protein-coupled receptor-associated sorting protein-1Carboxyl-terminal and intracellular loop sites for CRF1 receptor phosphorylation and beta-arrestin-2 recruitment: a mechanism regulating stress and anxiety responsesFew residues within an extensive binding interface drive receptor interaction and determine the specificity of arrestin proteins.β-Arrestin-mediated receptor trafficking and signal transductionCargo- and compartment-selective endocytic scaffold proteins.Altered functioning of both renal dopamine D1 and angiotensin II type 1 receptors causes hypertension in old rats.Reciprocal modulation of function between the D1 and D2 dopamine receptors and the Na+,K+-ATPaseProtein kinase D1-dependent phosphorylation of dopamine D1 receptor regulates cocaine-induced behavioral responses.Hypothesis review: are clathrin-mediated endocytosis and clathrin-dependent membrane and protein trafficking core pathophysiological processes in schizophrenia and bipolar disorder?Dopamine and renal function and blood pressure regulation.Beta-arrestin mediates desensitization and internalization but does not affect dephosphorylation of the thyrotropin-releasing hormone receptor.G protein-coupled receptor kinases as regulators of dopamine receptor functions.G Protein-Coupled Receptor Signaling Through β-Arrestin-Dependent Mechanisms.An intracellular loop 2 amino acid residue determines differential binding of arrestin to the dopamine D2 and D3 receptors.Dual role of the beta2-adrenergic receptor C terminus for the binding of beta-arrestin and receptor internalization.Ethanol regulation of D(1) dopamine receptor signaling is mediated by protein kinase C in an isozyme-specific manner.The third intracellular loop of the human somatostatin receptor 5 is crucial for arrestin binding and receptor internalization after somatostatin stimulation.Insulin causes renal dopamine D1 receptor desensitization via GRK2-mediated receptor phosphorylation involving phosphatidylinositol 3-kinase and protein kinase C.D1 and D2 dopamine receptor expression is regulated by direct interaction with the chaperone protein calnexin.Uncoupling and endocytosis of 5-hydroxytryptamine 4 receptors. Distinct molecular events with different GRK2 requirements.G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation.Detection of cell surface dopamine receptors.Targeting individual GPCRs with redesigned nonvisual arrestins.Characterization of [(3) H]LS-3-134, a novel arylamide phenylpiperazine D3 dopamine receptor selective radioligand.Role of Phosphorylation in the Control of Clathrin-Mediated Internalization of GPCR.NF-kappaB is dispensable for normal lymphocyte development in bone marrow but required for protection of progenitors from TNFalpha.Dopamine D1 receptor interaction with arrestin3 in neostriatal neurons.Detection of phasic dopamine by D1 and D2 striatal medium spiny neurons.
P2860
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P2860
The role of phosphorylation in D1 dopamine receptor desensitization: evidence for a novel mechanism of arrestin association
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
The role of phosphorylation in ...... hanism of arrestin association
@ast
The role of phosphorylation in ...... hanism of arrestin association
@en
type
label
The role of phosphorylation in ...... hanism of arrestin association
@ast
The role of phosphorylation in ...... hanism of arrestin association
@en
prefLabel
The role of phosphorylation in ...... hanism of arrestin association
@ast
The role of phosphorylation in ...... hanism of arrestin association
@en
P2093
P2860
P356
P1476
The role of phosphorylation in ...... hanism of arrestin association
@en
P2093
Benjamin R Gardner
Chun C Mak
Daniel B Williams
David M Cabrera
David R Sibley
Jennifer D Peters
Kyeong-Man Kim
Ok-Jin Kim
Paul S Marinec
P2860
P304
P356
10.1074/JBC.M308281200
P407
P577
2003-12-04T00:00:00Z