rag-1 and rag-2 are components of a high-molecular-weight complex, and association of rag-2 with this complex is rag-1 dependent.
about
Lambda5 is required for rearrangement of the Ig kappa light chain gene in pro-B cell linesThe XRCC4 gene product is a target for and interacts with the DNA-dependent protein kinaseThe RING finger protein SNURF is a bifunctional protein possessing DNA binding activityEmbryonic expression and regulation of the large zinc finger protein KRCMapping and Quantitation of the Interaction between the Recombination Activating Gene Proteins RAG1 and RAG2.Elucidating the domain architecture and functions of non-core RAG1: the capacity of a non-core zinc-binding domain to function in nuclear import and nucleic acid bindingInitiation of V(D)J recombination by Dbeta-associated recombination signal sequences: a critical control point in TCRbeta gene assemblyThe in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci.RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex.Detection of RAG protein-V(D)J recombination signal interactions near the site of DNA cleavage by UV cross-linking.RUNX1-dependent RAG1 deposition instigates human TCR-δ locus rearrangementV(D)J recombination frequency is affected by the sequence interposed between a pair of recombination signals: sequence comparison reveals a putative recombinational enhancer element.A variable immunoreceptor in a subpopulation of human neutrophils.Overlapping signals for protein degradation and nuclear localization define a role for intrinsic RAG-2 nuclear uptake in dividing cells.Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombination.In vitro and in vivo studies on the generation of the primary T-cell receptor repertoire.The bounty of RAGs: recombination signal complexes and reaction outcomes.In vitro V(D)J recombination: signal joint formation.Coding joint diversity in mature and immature B-cell lines.The half-life of RAG-1 protein in precursor B cells is increased in the absence of RAG-2 expression.T-cell receptor alpha locus V(D)J recombination by-products are abundant in thymocytes and mature T cells.Cryptic signals and the fidelity of V(D)J joining.A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity.V(D)J recombination: in vitro coding joint formation.Evidence for Ku70/Ku80 association with full-length RAG1.Cooperative recruitment of HMGB1 during V(D)J recombination through interactions with RAG1 and DNA.Karyopherin alpha 1 is a putative substrate of the RAG1 ubiquitin ligase.CD40 interacts directly with RAG1 and RAG2 in autoaggressive T cells and Fas prevents CD40-induced RAG expression.The roles of the RAG1 and RAG2 "non-core" regions in V(D)J recombination and lymphocyte development.RAG1-DNA binding in V(D)J recombination. Specificity and DNA-induced conformational changes revealed by fluorescence and CD spectroscopy.Modeling of the RAG reaction mechanism.Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells.The effect of Me2+ cofactors at the initial stages of V(D)J recombination.The effects of transfected mutant and wild type RAG genes in different cell types.Epstein-Barr virus infection of T cells: implications for altered T-lymphocyte activation, repertoire development and autoimmunity.Mmip-2, a novel RING finger protein that interacts with mad members of the Myc oncoprotein network.V(D)J recombination activity in human hematopoietic cells: correlation with developmental stage and genome stability.
P2860
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P2860
rag-1 and rag-2 are components of a high-molecular-weight complex, and association of rag-2 with this complex is rag-1 dependent.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
rag-1 and rag-2 are components ...... is complex is rag-1 dependent.
@ast
rag-1 and rag-2 are components ...... is complex is rag-1 dependent.
@en
type
label
rag-1 and rag-2 are components ...... is complex is rag-1 dependent.
@ast
rag-1 and rag-2 are components ...... is complex is rag-1 dependent.
@en
prefLabel
rag-1 and rag-2 are components ...... is complex is rag-1 dependent.
@ast
rag-1 and rag-2 are components ...... is complex is rag-1 dependent.
@en
P2860
P356
P1476
rag-1 and rag-2 are components ...... is complex is rag-1 dependent.
@en
P2093
P2860
P304
P356
10.1128/MCB.15.10.5657
P407
P577
1995-10-01T00:00:00Z