Role of Raf kinase in cancer: therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway.
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Regulation of mixed lineage kinase 3 is required for Neurofibromatosis-2-mediated growth suppression in human cancerMEK and PI3K inhibition in solid tumors: rationale and evidence to dateBiological features and biomarkers in hepatocellular carcinomaCurrent and future trials of targeted therapies in cutaneous melanomaNovel signaling pathways in pulmonary arterial hypertension (2015 Grover Conference Series)Bone marrow mononuclear cell transplantation promotes therapeutic angiogenesis via upregulation of the VEGF-VEGFR2 signaling pathway in a rat model of vascular dementiaDivergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor developmentProtein kinase R modulates c-Fos and c-Jun signaling to promote proliferation of hepatocellular carcinoma with hepatitis C virus infectionMetformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cellsThe study of a novel sorafenib derivative HLC-080 as an antitumor agentEvaluating Inhibition of the Epidermal Growth Factor (EGF)-Induced Response of Mutant MCF10A Cells with an Acoustic Sensor.Early MRI response monitoring of patients with advanced hepatocellular carcinoma under treatment with the multikinase inhibitor sorafenib.Cellular Ser/Thr-kinase assays using generic peptide substrates.Oncolytic Virus-Based Immunotherapies for Hepatocellular Carcinoma.Multikinase inhibitor sorafenib prevents pressure overload-induced left ventricular hypertrophy in rats by blocking the c-Raf/ERK1/2 signaling pathway.Evolving role of Sorafenib in the management of hepatocellular carcinoma.Targeted therapies for gastric cancer: current status.Sorafenib: complexities of Raf-dependent and Raf-independent signaling are now unveiled.Activation of the MEK-S6 pathway in high-grade ovarian cancers.Calcineurin increases glucose activation of ERK1/2 by reversing negative feedback.Computational design of a CNT carrier for a high affinity bispecific anti-HER2 antibody based on trastuzumab and pertuzumab Fabs.Targeting proapoptotic protein BAD inhibits survival and self-renewal of cancer stem cellsPazopanib reveals a role for tumor cell B-Raf in the prevention of HER2+ breast cancer brain metastasis.Berberine Targets AP-2/hTERT, NF-κB/COX-2, HIF-1α/VEGF and Cytochrome-c/Caspase Signaling to Suppress Human Cancer Cell Growth.Advanced urothelial carcinoma: next-generation sequencing reveals diverse genomic alterations and targets of therapy.Assessment of the Selenoprotein M (SELM) over-expression on human hepatocellular carcinoma tissues by immunohistochemistry.Early drug development of inhibitors of the insulin-like growth factor-I receptor pathway: lessons from the first clinical trials.An Update on the Biology of RAS/RAF Mutations in Colorectal Cancer.Clinical outcomes of patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective study of routine clinical practice in multi-institutionsmiR-27b controls venous specification and tip cell fateCombination of a Selective HSP90α/β Inhibitor and a RAS-RAF-MEK-ERK Signaling Pathway Inhibitor Triggers Synergistic Cytotoxicity in Multiple Myeloma Cells.ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristics.K-RAS GTPase- and B-RAF kinase-mediated T-cell tolerance defects in rheumatoid arthritis.The effects of sorafenib on liver regeneration in a model of partial hepatectomy.Development of a novel class of B-Raf(V600E)-selective inhibitors through virtual screening and hierarchical hit optimizationArray-based profiling of the differential methylation status of CpG islands in hepatocellular carcinoma cell lines.Targeting the MAPK-RAS-RAF signaling pathway in cancer therapyExperience with sorafenib in the treatment of advanced renal cell carcinoma.K-Ras gene mutation status as a prognostic and predictive factor in patients with colorectal cancer undergoing irinotecan- or oxaliplatin-based chemotherapySynergistic effect of pasireotide and teriflunomide in carcinoids in vitro.
P2860
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P2860
Role of Raf kinase in cancer: therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Role of Raf kinase in cancer: ...... K signal transduction pathway.
@ast
Role of Raf kinase in cancer: ...... K signal transduction pathway.
@en
type
label
Role of Raf kinase in cancer: ...... K signal transduction pathway.
@ast
Role of Raf kinase in cancer: ...... K signal transduction pathway.
@en
prefLabel
Role of Raf kinase in cancer: ...... K signal transduction pathway.
@ast
Role of Raf kinase in cancer: ...... K signal transduction pathway.
@en
P2093
P1433
P1476
Role of Raf kinase in cancer: ...... K signal transduction pathway.
@en
P2093
Chris Carter
Jared A Gollob
Scott Wilhelm
Susan L Kelley
P304
P356
10.1053/J.SEMINONCOL.2006.04.002
P577
2006-08-01T00:00:00Z