Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network
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MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cellsMet-HGF/SF signal transduction induces mimp, a novel mitochondrial carrier homologue, which leads to mitochondrial depolarizationNeutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal modelsMET: a critical player in tumorigenesis and therapeutic targetRole of mesenchymal-epithelial transition amplification in resistance to anti-epidermal growth factor receptor agentsMet receptor tyrosine kinase: enhanced signaling through adapter proteinsNK4 (HGF-antagonist/angiogenesis inhibitor) in cancer biology and therapeuticsHGF/SF-met signaling in the control of branching morphogenesis and invasionHepatocyte growth factor/scatter factor binds with high affinity to dermatan sulfatePAI-1 expression is required for epithelial cell migration in two distinct phases of in vitro wound repairTherapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models: preclinical study for treatment of peripheral arterial disease.HGF/SF activates glycolysis and oxidative phosphorylation in DA3 murine mammary cancer cells.Src homology 2-containing inositol 5-phosphatase 1 binds to the multifunctional docking site of c-Met and potentiates hepatocyte growth factor-induced branching tubulogenesis.Actions of heparin that may affect the malignant process.An orally available small-molecule inhibitor of c-Met, PF-2341066, reduces tumor burden and metastasis in a preclinical model of ovarian cancer metastasis.HGF/Met Signaling in Cancer Invasion: The Impact on Cytoskeleton Remodeling.Disassociation of met-mediated biological responses in vivo: the natural hepatocyte growth factor/scatter factor splice variant NK2 antagonizes growth but facilitates metastasis.Regulation of P311 expression by Met-hepatocyte growth factor/scatter factor and the ubiquitin/proteasome system.Proliferation and invasion: plasticity in tumor cells.Hepatocyte growth factor promotes lymphatic vessel formation and function.The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cellsOverexpression of c-Met increases the tumor invasion of human prostate LNCaP cancer cells in vitro and in vivoA novel multipurpose monoclonal antibody for evaluating human c-Met expression in preclinical and clinical settings.Met protein and hepatocyte growth factor (HGF) in papillary carcinoma of the thyroid: evidence for a pathogenetic role in tumourigenesis.Overexpression of sprouty 2 inhibits HGF/SF-mediated cell growth, invasion, migration, and cytokinesis.The HGF receptor c-Met is overexpressed in esophageal adenocarcinoma.Activation of hepatocyte growth factor-met autocrine loop enhances tumorigenicity in a human lung adenocarcinoma cell line.Suppression of ras-mediated transformation and inhibition of tumor growth and angiogenesis by anthrax lethal factor, a proteolytic inhibitor of multiple MEK pathwaysThe plasminogen activation system reduces fibrosis in the lung by a hepatocyte growth factor-dependent mechanism.Foretinib (GSK1363089), an orally available multikinase inhibitor of c-Met and VEGFR-2, blocks proliferation, induces anoikis, and impairs ovarian cancer metastasis.Down-regulation of survivin suppresses uro-plasminogen activator through transcription factor JunBHepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma.Activation of the urokinase plasminogen activator/urokinase plasminogen activator receptor system and redistribution of E-cadherin are associated with hepatocyte growth factor-induced motility of pancreas tumor cells overexpressing Met.Expression of Met/hepatocyte growth factor receptor gene and malignant behavior of musculoskeletal tumors.Effect of SNC19/ST14 gene overexpression on invasion of colorectal cancer cells.Chromosome instability, chromosome transcriptome, and clonal evolution of tumor cell populations.Expression of c-Met and heparan-sulfate proteoglycan forms of CD44 in colorectal cancerFibroblasts--a key host cell type in tumor initiation, progression, and metastasis.HGF stimulates proliferation through the HGF/c-Met pathway in nasopharyngeal carcinoma cellsSignaling pathways in Ras-mediated tumorigenicity and metastasis.
P2860
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P2860
Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Enhanced tumorigenicity and in ...... urokinase proteolysis network
@ast
Enhanced tumorigenicity and in ...... urokinase proteolysis network
@en
type
label
Enhanced tumorigenicity and in ...... urokinase proteolysis network
@ast
Enhanced tumorigenicity and in ...... urokinase proteolysis network
@en
prefLabel
Enhanced tumorigenicity and in ...... urokinase proteolysis network
@ast
Enhanced tumorigenicity and in ...... urokinase proteolysis network
@en
P2093
P2860
P356
P1476
Enhanced tumorigenicity and in ...... urokinase proteolysis network
@en
P2093
P2860
P304
P356
10.1128/MCB.16.3.1115
P407
P577
1996-03-01T00:00:00Z