Overexpression of sprouty 2 inhibits HGF/SF-mediated cell growth, invasion, migration, and cytokinesis. - Wikidata - awgldk - TriplyDB

Overexpression of sprouty 2 inhibits HGF/SF-mediated cell growth, invasion, migration, and cytokinesis.

Overexpression of sprouty 2 inhibits HGF/SF-mediated cell growth, invasion, migration, and cytokinesis.

http://www.wikidata.org/entity/Q34318050

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A novel role of Sprouty 2 in regulating cellular apoptosis MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy Drug and bioactive molecule screening based on a bioelectrical impedance cell culture platform.A functional interaction between sprouty proteins and caveolin-1 Systematic analysis of copy number variants of a large cohort of orofacial cleft patients identifies candidate genes for orofacial clefts.Regulation of sprouty stability by Mnk1-dependent phosphorylation.Noncoding mutations of HGF are associated with nonsyndromic hearing loss, DFNB39.Cell migration regulates the kinetics of cytokinesis.Identification and analysis of tumour-associated antigens in hepatocellular carcinoma.HECT domain-containing E3 ubiquitin ligase Nedd4 interacts with and ubiquitinates Sprouty2.CtBP1 interacts with Ikaros and modulates pituitary tumor cell survival and response to hypoxia The expression of the Sprouty 1 protein inversely correlates with growth, proliferation, migration and invasion of ovarian cancer cells Modifications in host cell cytoskeleton structure and function mediated by intracellular HIV-1 Tat protein are greatly dependent on the second coding exon FGF signaling regulates the number of posterior taste papillae by controlling progenitor field size.The developing story of Sprouty and cancer.Synergistic role of Sprouty2 inactivation and c-Met up-regulation in mouse and human hepatocarcinogenesis.Functional interaction between Env oncogene from Jaagsiekte sheep retrovirus and tumor suppressor Sprouty2.Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation.Spred-1 negatively regulates interleukin-3-mediated ERK/mitogen-activated protein (MAP) kinase activation in hematopoietic cells.Sprouty2 mediated tuning of signalling is essential for somite myogenesis.Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile HGF/SF-Met signaling in tumor progression.E3 ubiquitin ligases as regulators of membrane protein trafficking and degradation.Sprouty is a negative regulator of transforming growth factor β-induced epithelial-to-mesenchymal transition and cataract.Automated time-lapse microscopy and high-resolution tracking of cell migration.Hypoxia inducible factors regulate the transcription of the sprouty2 gene and expression of the sprouty2 protein Fibrosis in the lens. Sprouty regulation of TGFβ-signaling prevents lens EMT leading to cataract.Initial report on differential expression of sprouty proteins 1 and 2 in human epithelial ovarian cancer cell lines.Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression.From Tpr-Met to Met, tumorigenesis and tubes.c-MYC-regulated miR-23a/24-2/27a cluster promotes mammary carcinoma cell invasion and hepatic metastasis by targeting Sprouty2.Sprouty 2 regulates DNA damage-induced apoptosis in Ras-transformed human fibroblasts.Overexpression of Sprouty 2 in mouse lung epithelium inhibits urethane-induced tumorigenesis Intermolecular interactions of Sprouty proteins and their implications in development and disease.Progress in cancer therapy targeting c-Met signaling pathway.MT1-MMP dependent repression of the tumor suppressor SPRY4 contributes to MT1-MMP driven melanoma cell motility.Tetraspanin CD82: a suppressor of solid tumors and a modulator of membrane heterogeneity.Loss of Sprouty2 in human high-grade serous ovarian carcinomas promotes EGF-induced E-cadherin down-regulation and cell invasion.Modulation of ERK5 is a novel mechanism by which Cdc42 regulates migration of breast cancer cells.

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P2860

Overexpression of sprouty 2 inhibits HGF/SF-mediated cell growth, invasion, migration, and cytokinesis.

http://www.wikidata.org/entity/Q34318050

description

2004 nî lūn-bûn

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2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2004 թվականի հուլիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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Overexpression of sprouty 2 in ...... n, migration, and cytokinesis.

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Overexpression of sprouty 2 in ...... n, migration, and cytokinesis.

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Overexpression of sprouty 2 in ...... n, migration, and cytokinesis.

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type

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Overexpression of sprouty 2 in ...... n, migration, and cytokinesis.

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Overexpression of sprouty 2 in ...... n, migration, and cytokinesis.

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Overexpression of sprouty 2 in ...... n, migration, and cytokinesis.

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Overexpression of sprouty 2 in ...... on, migration, and cytokinesis

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Chong-Chou Lee

http://www.w3.org/2001/XMLSchema#string

Chong-Feng Gao

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Cindy K Miranti

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George F Vande Woude

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Ling-Mei Wang

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Margaret Gustafson

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P2860

Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function

sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways

The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins

Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling.

The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met

Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein

Met, metastasis, motility and more

Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation

Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis

Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis

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10.1038/SJ.ONC.1207646

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30

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23

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Andrew J Putnam

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2004-07-01T00:00:00Z

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8583749

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15122328

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