Activation of the lifespan regulator p66Shc through reversible disulfide bond formation.
about
Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancersSHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegansRole of ROS and RNS Sources in Physiological and Pathological ConditionsMitochondrial Oxidative Stress, Mitochondrial DNA Damage and Their Role in Age-Related Vascular DysfunctionRedox modification of proteins as essential mediators of CNS autophagy and mitophagy.Redox regulation of mitochondrial functionReactive oxygen species (ROS) homeostasis and redox regulation in cellular signalingThioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signalingA phosphodiesterase 2A isoform localized to mitochondria regulates respirationIdentification of Peroxiredoxin 1 as a novel interaction partner for the lifespan regulator protein p66Shc.Redox-regulated chaperones.p66Shc--a longevity redox protein in human prostate cancer progression and metastasis : p66Shc in cancer progression and metastasis.Deletion of p66Shc in mice increases the frequency of size-change mutations in the lacZ transgeneNitroalkenes confer acute cardioprotection via adenine nucleotide translocase 1.p66ShcA promotes breast cancer plasticity by inducing an epithelial-to-mesenchymal transition.Sulfhydration of p66Shc at cysteine59 mediates the antioxidant effect of hydrogen sulfide.Prooxidant properties of p66shc are mediated by mitochondria in human cellsSignaling and Damaging Functions of Free Radicals in Aging-Free Radical Theory, Hormesis, and TOR.Thioredoxin-2 Modulates Neuronal Programmed Cell Death in the Embryonic Chick Spinal Cord in Basal and Target-Deprived ConditionsThe P66Shc/mitochondrial permeability transition pore pathway determines neurodegeneration.Regulation of reactive oxygen species generation in cell signaling.Disulfide formation in the ER and mitochondria: two solutions to a common process.The p66(Shc) adaptor protein controls oxidative stress response in early bovine embryos.Role of Mitochondria-Associated Endoplasmic Reticulum Membrane in Inflammation-Mediated Metabolic DiseasesMitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling.The Role of p66shc in Oxidative Stress and Apoptosis.Teaching an old dogma new tricks: twenty years of Shc adaptor signalling.Modelling the p53/p66Shc Aging Pathway in the Shortest Living Vertebrate Nothobranchius Furzeri.Expression, purification, crystallization and preliminary X-ray diffraction analysis of a mammalian type 10 adenylyl cyclase.Vitamin A as PKC Co-factor and Regulator of Mitochondrial Energetics.Reactive oxygen species and age-related genes p66shc, Sirtuin, FOX03 and Klotho in senescence.Measuring p66Shc Signaling Pathway Activation and Mitochondrial Translocation in Cultured Cells.Insights into the Shc Family of Adaptor Proteins.Redox crosstalk at endoplasmic reticulum (ER) membrane contact sites (MCS) uses toxic waste to deliver messages.
P2860
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P2860
Activation of the lifespan regulator p66Shc through reversible disulfide bond formation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Activation of the lifespan regulator p66Shc through reversible disulfide bond formation.
@ast
Activation of the lifespan regulator p66Shc through reversible disulfide bond formation.
@en
type
label
Activation of the lifespan regulator p66Shc through reversible disulfide bond formation.
@ast
Activation of the lifespan regulator p66Shc through reversible disulfide bond formation.
@en
prefLabel
Activation of the lifespan regulator p66Shc through reversible disulfide bond formation.
@ast
Activation of the lifespan regulator p66Shc through reversible disulfide bond formation.
@en
P2093
P2860
P356
P1476
Activation of the lifespan regulator p66Shc through reversible disulfide bond formation.
@en
P2093
Clemens Steegborn
Dirk Wolters
Frank Fischer
Melanie Gertz
P2860
P304
P356
10.1073/PNAS.0800691105
P407
P577
2008-04-14T00:00:00Z