Inactivation of a human kinetochore by specific targeting of chromatin modifiers.
about
Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomesPremitotic assembly of human CENPs -T and -W switches centromeric chromatin to a mitotic stateA new generation of human artificial chromosomes for functional genomics and gene therapyHuman artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cellsA highly stable and nonintegrated human artificial chromosome (HAC) containing the 2.4 Mb entire human dystrophin geneA pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challengesQuantitative assessment of chromosome instability induced through chemical disruption of mitotic progressionATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cellsDualistic function of Daxx at centromeric and pericentromeric heterochromatin in normal and stress conditionsComparative analysis of tandem repeats from hundreds of species reveals unique insights into centromere evolutionHIV infection reveals widespread expansion of novel centromeric human endogenous retrovirusesAccelerated evolution of the Prdm9 speciation gene across diverse metazoan taxaDevelopment of a novel HAC-based "gain of signal" quantitative assay for measuring chromosome instability (CIN) in cancer cellsIdentification of the Post-translational Modifications Present in Centromeric ChromatinMitotic noncoding RNA processing promotes kinetochore and spindle assembly in Xenopus.Putting CENP-A in its placeHJURP is a CENP-A chromatin assembly factor sufficient to form a functional de novo kinetochore.Assembling pieces of the centromere epigenetics puzzle.Intergenic locations of rice centromeric chromatin.Neocentromeres form efficiently at multiple possible loci in Candida albicans.HAC stability in murine cells is influenced by nuclear localization and chromatin organization.Histone modifications within the human X centromere region.A cell-free system for functional centromere and kinetochore assemblyIdentification of a maize neocentromere in an oat-maize addition line.RNA stimulates Aurora B kinase activity during mitosis.CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses.Histone H4 Lys 20 monomethylation of the CENP-A nucleosome is essential for kinetochore assembly.A super-resolution map of the vertebrate kinetochore.Bi-HAC vector system toward gene and cell therapyThe centromere: chromatin foundation for the kinetochore machinery.Centromeres: unique chromatin structures that drive chromosome segregation.Human artificial chromosome with a conditional centromere for gene delivery and gene expression.Replication of alpha-satellite DNA arrays in endogenous human centromeric regions and in human artificial chromosomeA novel system for simultaneous or sequential integration of multiple gene-loading vectors into a defined site of a human artificial chromosomeChromosome engineering allows the efficient isolation of vertebrate neocentromeres.Neocentromeres: a place for everything and everything in its placeCentromere architecture breakdown induced by the viral E3 ubiquitin ligase ICP0 protein of herpes simplex virus type 1.Sequence features and transcriptional stalling within centromere DNA promote establishment of CENP-A chromatin.Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochoreCentromeric heterochromatin: the primordial segregation machine.
P2860
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P2860
Inactivation of a human kinetochore by specific targeting of chromatin modifiers.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Inactivation of a human kinetochore by specific targeting of chromatin modifiers.
@ast
Inactivation of a human kinetochore by specific targeting of chromatin modifiers.
@en
type
label
Inactivation of a human kinetochore by specific targeting of chromatin modifiers.
@ast
Inactivation of a human kinetochore by specific targeting of chromatin modifiers.
@en
prefLabel
Inactivation of a human kinetochore by specific targeting of chromatin modifiers.
@ast
Inactivation of a human kinetochore by specific targeting of chromatin modifiers.
@en
P2093
P2860
P50
P1433
P1476
Inactivation of a human kinetochore by specific targeting of chromatin modifiers.
@en
P2093
Hiroshi Masumoto
Megumi Nakano
Paola Vagnarelli
Stefanie Kandels-Lewis
Vladimir Larionov
Vladimir N Noskov
P2860
P304
P356
10.1016/J.DEVCEL.2008.02.001
P407
P577
2008-04-01T00:00:00Z