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Thermodynamic analysis shows conformational coupling and dynamics confer substrate specificity in fructose-1,6-bisphosphate aldolasePhysicochemical Properties of Ion Pairs of Biological MacromoleculesHomotropic allosteric regulation in monomeric mammalian glucokinaseConformational selection in protein binding and functionShedding light on protein folding, structural and functional dynamics by single molecule studiesAllosteric activation transitions in enzymes and biomolecular motors: insights from atomistic and coarse-grained simulationsEvolutionarily conserved linkage between enzyme fold, flexibility, and catalysisDiscovering conformational sub-states relevant to protein functionConformational Isomerism Can Limit Antibody CatalysisFunctional and Structural Roles of the Cys14–Cys38 Disulfide of Bovine Pancreatic Trypsin InhibitorEnzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selectionSolution Structure and Backbone Dynamics of Streptopain: INSIGHT INTO DIVERSE SUBSTRATE SPECIFICITYHydrogen Bond Coupling in the Ketosteroid Isomerase Active SitePressure-Dependent Structure Changes in Barnase on Ligand Binding Reveal Intermediate Rate FluctuationsThe Crystal Structure of the Novobiocin Biosynthetic Enzyme NovP: The First Representative Structure for the TylF O-Methyltransferase SuperfamilyLarge-scale Domain Dynamics and Adenosylcobalamin Reorientation Orchestrate Radical Catalysis in Ornithine 4,5-AminomutaseCoupling of receptor conformation and ligand orientation determine graded activityComparison of NMR and crystal structures highlights conformational isomerism in protein active sitesArginine Kinase: Joint Crystallographic and NMR RDC Analyses Link Substrate-Associated Motions to Intrinsic FlexibilityThe Structure of Lombricine Kinase: IMPLICATIONS FOR PHOSPHAGEN KINASE CONFORMATIONAL CHANGESSolution Structures of Ca 2+ -CIB1 and Mg 2+ -CIB1 and Their Interactions with the Platelet Integrin αIIb Cytoplasmic DomainIntegrin α1 Has a Long Helix, Extending from the Transmembrane Region to the Cytoplasmic Tail in Detergent MicellesUltrahigh and High Resolution Structures and Mutational Analysis of Monomeric Streptococcus pyogenes SpeB Reveal a Functional Role for the Glycine-rich C-terminal LoopExploring the role of conformational heterogeneity in cis-autoproteolytic activation of ThnT.The importance of ensemble averaging in enzyme kineticsAt the dawn of the 21st century: Is dynamics the missing link for understanding enzyme catalysis?Interconversion of functional motions between mesophilic and thermophilic adenylate kinasesThermal adaptation of conformational dynamics in ribonuclease HPreservation of protein dynamics in dihydrofolate reductase evolutionA decade and a half of protein intrinsic disorder: biology still waits for physicsPerspective: Defining and quantifying the role of dynamics in enzyme catalysisThe role of dynamic conformational ensembles in biomolecular recognitionProteins at work: a combined small angle X-RAY scattering and theoretical determination of the multiple structures involved on the protein kinase functional landscapeNative state dynamics drive the unfolding of the SH3 domain of PI3 kinase at high denaturant concentration.Computational identification of slow conformational fluctuations in proteinsPredicting protein flexibility through the prediction of local structures.All-atom modeling of anisotropic atomic fluctuations in protein crystal structures.Protein dynamics studied with ultrafast two-dimensional infrared vibrational echo spectroscopy.The quiet renaissance of protein nuclear magnetic resonance.Mapping molecular flexibility of proteins with site-directed spin labeling: a case study of myoglobin.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
An NMR perspective on enzyme dynamics.
@ast
An NMR perspective on enzyme dynamics.
@en
type
label
An NMR perspective on enzyme dynamics.
@ast
An NMR perspective on enzyme dynamics.
@en
prefLabel
An NMR perspective on enzyme dynamics.
@ast
An NMR perspective on enzyme dynamics.
@en
P356
P1433
P1476
An NMR perspective on enzyme dynamics.
@en
P2093
David D Boehr
P304
P356
10.1021/CR050312Q
P577
2006-08-01T00:00:00Z