The immunosuppressant SR 31747 blocks cell proliferation by inhibiting a steroid isomerase in Saccharomyces cerevisiae.
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ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesisPurification and characterization of the human SR 31747A-binding protein. A nuclear membrane protein related to yeast sterol isomeraseTsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiaeLarge-scale phenotypic analysis--the pilot project on yeast chromosome III.Involvement of long chain fatty acid elongation in the trafficking of secretory vesicles in yeastThe effect of the erg26-1 mutation on the regulation of lipid metabolism in Saccharomyces cerevisiae.The fenpropimorph resistance gene FEN2 from Saccharomyces cerevisiae encodes a plasma membrane H+-pantothenate symporter.ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation.How to bring orphan genes into functional families.Emopamil-binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits delta8-delta7 sterol isomerase activity in yeastCandida albicans sterol C-14 reductase, encoded by the ERG24 gene, as a potential antifungal target siteSyringomycin E inhibition of Saccharomyces cerevisiae: requirement for biosynthesis of sphingolipids with very-long-chain fatty acids and mannose- and phosphoinositol-containing head groups.Electrospray ionization tandem mass spectrometry (ESI-MS/MS) analysis of the lipid molecular species composition of yeast subcellular membranes reveals acyl chain-based sorting/remodeling of distinct molecular species en route to the plasma membraneThe yeast sphingolipid signaling landscape.A specific structural requirement for ergosterol in long-chain fatty acid synthesis mutants important for maintaining raft domains in yeast.A Saccharomyces cerevisiae mutant strain defective in acetyl-CoA carboxylase arrests at the G2/M phase of the cell cycle.High affinity of sigma 1-binding sites for sterol isomerization inhibitors: evidence for a pharmacological relationship with the yeast sterol C8-C7 isomeraseCumulative mutations affecting sterol biosynthesis in the yeast Saccharomyces cerevisiae result in synthetic lethality that is suppressed by alterations in sphingolipid profiles.Role of the non-respiratory pathways in the utilization of molecular oxygen by Saccharomyces cerevisiae.A female-biased expressed elongase involved in long-chain hydrocarbon biosynthesis and courtship behavior in Drosophila melanogasterIdentification of Yeast Mutants Exhibiting Altered Sensitivity to Valinomycin and Nigericin Demonstrate Pleiotropic Effects of Ionophores on Cellular Processes.Two clinical isolates of Candida glabrata exhibiting reduced sensitivity to amphotericin B both harbor mutations in ERG2.SR31747A is a sigma receptor ligand exhibiting antitumoural activity both in vitro and in vivo.A DNA microarray-based approach to elucidate the effects of the immunosuppressant SR31747A on gene expression in Saccharomyces cerevisiae.Genomic approach to identification of mutations affecting caspofungin susceptibility in Saccharomyces cerevisiae.Yeast sphingolipids do not need to contain very long chain fatty acids.Synthetically lethal interactions involving loss of the yeast ERG24: the sterol C-14 reductase geneRole of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids.Immunocytochemical assessment of sigma-1 receptor and human sterol isomerase in breast cancer and their relationship with a series of prognostic factors.Sterol-dependent regulation of sphingolipid metabolism in Saccharomyces cerevisiae.Effects of distal cholesterol biosynthesis inhibitors on cell proliferation and cell cycle progression.hydra Mutants of Arabidopsis are defective in sterol profiles and auxin and ethylene signaling.Increasing medium chain fatty acids production in Yarrowia lipolytica by metabolic engineering
P2860
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P2860
The immunosuppressant SR 31747 blocks cell proliferation by inhibiting a steroid isomerase in Saccharomyces cerevisiae.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
The immunosuppressant SR 31747 ...... e in Saccharomyces cerevisiae.
@ast
The immunosuppressant SR 31747 ...... e in Saccharomyces cerevisiae.
@en
type
label
The immunosuppressant SR 31747 ...... e in Saccharomyces cerevisiae.
@ast
The immunosuppressant SR 31747 ...... e in Saccharomyces cerevisiae.
@en
prefLabel
The immunosuppressant SR 31747 ...... e in Saccharomyces cerevisiae.
@ast
The immunosuppressant SR 31747 ...... e in Saccharomyces cerevisiae.
@en
P2093
P2860
P356
P1476
The immunosuppressant SR 31747 ...... e in Saccharomyces cerevisiae.
@en
P2093
Leplatois P
P2860
P304
P356
10.1128/MCB.16.6.2719
P407
P577
1996-06-01T00:00:00Z