High affinity of sigma 1-binding sites for sterol isomerization inhibitors: evidence for a pharmacological relationship with the yeast sterol C8-C7 isomerase
about
Molecular cloning and expression of the human delta7-sterol reductaseThe hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulatorThe sigma receptor: evolution of the concept in neuropsychopharmacologyThe Therapeutic Potentials of Ayahuasca: Possible Effects against Various Diseases of CivilizationThe Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human FibroblastsProbing the steroid binding domain-like I (SBDLI) of the sigma-1 receptor binding site using N-substituted photoaffinity labels.A Review of the Human Sigma-1 Receptor Structure.The sigma-1 receptor chaperone as an inter-organelle signaling modulatorDueling enigmas: neurosteroids and sigma receptors in the limelight.Cholesterol at the endoplasmic reticulum: roles of the sigma-1 receptor chaperone and implications thereof in human diseases.The sigma1 receptor interacts with N-alkyl amines and endogenous sphingolipids.Characterization of interactions of 4-nitrophenylpropyl-N-alkylamine with ς receptors.The ligand binding region of the sigma-1 receptor: studies utilizing photoaffinity probes, sphingosine and N-alkylamines.Pharmacological profile and clinical use of moexipril.Connecting proteins with drug-like compounds: Open source drug discovery workflows with BindingDB and KNIME.Synthesis and characterization of N,N-dialkyl and N-alkyl-N-aralkyl fenpropimorph-derived compounds as high affinity ligands for sigma receptors.The cell death response to gamma-radiation in MCF-7 cells is enhanced by a neuroleptic drug, pimozide.Sigma receptors [σRs]: biology in normal and diseased statesVoltage-gated sodium channel modulation by sigma-receptors in cardiac myocytes and heterologous systems.Pharmacology and therapeutic potential of sigma(1) receptor ligands.Isolating and characterizing three alternatively spliced mu opioid receptor variants: mMOR-1A, mMOR-1O, and mMOR-1P.Sigma receptors and their ligands in cancer biology: overview and new perspectives for cancer therapy.Defects in cholesterol synthesis genes in mouse and in humans: lessons for drug development and safer treatments.Effect of different concentrations of oxygen on expression of sigma 1 receptor and superoxide dismutases in human colon adenocarcinoma cell lines.Sigma-1 receptor expression in the dorsal root ganglion: Reexamination using a highly specific antibody.Homology Model and Docking-Based Virtual Screening for Ligands of the σ1 Receptor.Juxtaposition of the steroid binding domain-like I and II regions constitutes a ligand binding site in the sigma-1 receptor.Purification and characterization of the guinea pig sigma-1 receptor functionally expressed in Escherichia coli.The sigma-1 receptor modulates NMDA receptor synaptic transmission and plasticity via SK channels in rat hippocampus.Altered expression level of Sigma1 receptor gene in human colorectal cancer.Are sigma receptor modulators a weapon against multiple sclerosis disease?3D Homology Model of Sigma1 Receptor.Modulation of steroidal levels by adrenalectomy/castration and inhibition of neurosteroid synthesis enzymes affect sigma1 receptor-mediated behaviour in mice.High-throughput screen for compounds that modulate neurite growth of human induced pluripotent stem cell derived neurons.Comparison of in Silico, Electrochemical, in Vitro and in Vivo Metabolism of a Homologous Series of (Radio)fluorinated σ1 Receptor Ligands Designed for Positron Emission Tomography.The Role of Sigma-1 Receptor, an Intracellular Chaperone in Neurodegenerative Diseases.
P2860
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P2860
High affinity of sigma 1-binding sites for sterol isomerization inhibitors: evidence for a pharmacological relationship with the yeast sterol C8-C7 isomerase
description
1997 nî lūn-bûn
@nan
1997 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
High affinity of sigma 1-bindi ...... e yeast sterol C8-C7 isomerase
@ast
High affinity of sigma 1-bindi ...... e yeast sterol C8-C7 isomerase
@en
type
label
High affinity of sigma 1-bindi ...... e yeast sterol C8-C7 isomerase
@ast
High affinity of sigma 1-bindi ...... e yeast sterol C8-C7 isomerase
@en
prefLabel
High affinity of sigma 1-bindi ...... e yeast sterol C8-C7 isomerase
@ast
High affinity of sigma 1-bindi ...... e yeast sterol C8-C7 isomerase
@en
P2093
P356
P1476
High affinity of sigma 1-bindi ...... e yeast sterol C8-C7 isomerase
@en
P2093
F F Moebius
H Glossmann
R J Reiter
P2860
P356
10.1038/SJ.BJP.0701079
P407
P577
1997-05-01T00:00:00Z