Oligodeoxynucleotide binding to (CTG) · (CAG) microsatellite repeats inhibits replication fork stalling, hairpin formation, and genome instability.
about
Replication fork instability and the consequences of fork collisions from rereplicationMutSβ promotes trinucleotide repeat expansion by recruiting DNA polymerase β to nascent (CAG)n or (CTG)n hairpins for error-prone DNA synthesisFANCJ is essential to maintain microsatellite structure genome-wide during replication stress.Replication stalling and DNA microsatellite instability.Break-induced replication links microsatellite expansion to complex genome rearrangements.Hypothesis: local dNTP depletion as the cause of microsatellite repeat instability during replication (comment on DOI 10.1002/bies.201200128).Expansion of CAG repeats in Escherichia coli is controlled by single-strand DNA exonucleases of both polarities.Functional Mechanisms of Microsatellite DNA in Eukaryotic Genomes.
P2860
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P2860
Oligodeoxynucleotide binding to (CTG) · (CAG) microsatellite repeats inhibits replication fork stalling, hairpin formation, and genome instability.
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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2012年论文
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2012年论文
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name
Oligodeoxynucleotide binding t ...... ation, and genome instability.
@ast
Oligodeoxynucleotide binding t ...... ation, and genome instability.
@en
type
label
Oligodeoxynucleotide binding t ...... ation, and genome instability.
@ast
Oligodeoxynucleotide binding t ...... ation, and genome instability.
@en
prefLabel
Oligodeoxynucleotide binding t ...... ation, and genome instability.
@ast
Oligodeoxynucleotide binding t ...... ation, and genome instability.
@en
P2093
P2860
P356
P1476
Oligodeoxynucleotide binding t ...... ation, and genome instability.
@en
P2093
Michael Leffak
Xiaomi Chen
P2860
P304
P356
10.1128/MCB.01265-12
P407
P577
2012-11-19T00:00:00Z