Inhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein.
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TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpressionInteraction of human thymidine kinase 1 with p21(Waf1)E2F activity is regulated by cell cycle-dependent changes in subcellular localizationp21cip1 is required for the differentiation of oligodendrocytes independently of cell cycle withdrawal.Selective cleavage of BLM, the bloom syndrome protein, during apoptotic cell death.Evidence that proteasome-dependent degradation of the retinoblastoma protein in cells lacking A-type lamins occurs independently of gankyrin and MDM2.The human papillomavirus type 58 E7 oncoprotein modulates cell cycle regulatory proteins and abrogates cell cycle checkpoints.A node between proliferation, apoptosis, and growth arrest.Regulation of the G1 phase of the mammalian cell cycle.Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor.Defect in the p53-Mdm2 autoregulatory loop resulting from inactivation of TAF(II)250 in cell cycle mutant tsBN462 cells.E2F4 is exported from the nucleus in a CRM1-dependent manner.Gene expression deregulation in postnatal skeletal muscle of TK2 deficient mice reveals a lower pool of proliferating myogenic progenitor cells.Biliverdin reductase A in the prevention of cellular senescence against oxidative stress.Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein.Stabilization of the retinoblastoma protein by A-type nuclear lamins is required for INK4A-mediated cell cycle arrestThe p21Waf1 pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO.Functional efficiency of the senescent cells: replace or restore?Initiation of DNA synthesis by human papillomavirus E7 oncoproteins is resistant to p21-mediated inhibition of cyclin E-cdk2 activityp53-Regulated Networks of Protein, mRNA, miRNA, and lncRNA Expression Revealed by Integrated Pulsed Stable Isotope Labeling With Amino Acids in Cell Culture (pSILAC) and Next Generation Sequencing (NGS) Analysesp21 suppresses inflammation and tumorigenesis on pRB-deficient stratified epithelia.Downregulation of p21/WAF1 is related to advanced and dedifferentiated laryngeal squamous cell carcinomap21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway.Downregulation of cyclin-dependent kinase 2 activity and cyclin A promoter activity in vascular smooth muscle cells by p27(KIP1), an inhibitor of neointima formation in the rat carotid artery.Senescence and p130/Rbl2: a new beginning to the end.Skin Tumors Rb(eing) Uncovered.Regulation of dihydrofolate reductase gene expression and E2F components in human diploid fibroblasts during growth and senescence.P130 and its truncated form mediate p53-induced cell cycle arrest in Rb(-/-) Saos2 cells.p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway.Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells.Ginsenoside Rb1, Rg1 and three extracts of traditional Chinese medicine attenuate ultraviolet B-induced G1 growth arrest in HaCaT cells and dermal fibroblasts involve down-regulating the expression of p16, p21 and p53.Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes.Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors.p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells.Induction of apoptosis by the transactivating domains of the hepatitis B virus X gene leads to suppression of oncogenic transformation of primary rat embryo fibroblasts.p53-dependent G2 arrest associated with a decrease in cyclins A2 and B1 levels in a human carcinoma cell lineMolecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins.Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication.Activation of p53-p21waf1 pathway in response to disruption of cell-matrix interactions.Formation of the early-region-2 transcription-factor-1-retinoblastoma-protein (E2F-1-RB) transrepressor and release of the retinoblastoma protein from nuclear complexes containing cyclin A is induced by interferon alpha in U937V cells but not in int
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P2860
Inhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Inhibition of E2F activity by ...... tional retinoblastoma protein.
@ast
Inhibition of E2F activity by ...... tional retinoblastoma protein.
@en
type
label
Inhibition of E2F activity by ...... tional retinoblastoma protein.
@ast
Inhibition of E2F activity by ...... tional retinoblastoma protein.
@en
prefLabel
Inhibition of E2F activity by ...... tional retinoblastoma protein.
@ast
Inhibition of E2F activity by ...... tional retinoblastoma protein.
@en
P2093
P2860
P356
P1476
Inhibition of E2F activity by ...... tional retinoblastoma protein.
@en
P2093
M Nakanishi
P Y Desprez
P2860
P304
P356
10.1128/MCB.16.6.2987
P407
P577
1996-06-01T00:00:00Z