The immediate-early gene product Egr-1 regulates the human interleukin-2 receptor beta-chain promoter through noncanonical Egr and Sp1 binding sites.
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The gene for interleukin-21 receptor is the partner of BCL6 in t(3;16)(q27;p11), which is recurrently observed in diffuse large B-cell lymphomaCo-operative interactions between NFAT (nuclear factor of activated T cells) c1 and the zinc finger transcription factors Sp1/Sp3 and Egr-1 regulate MT1-MMP (membrane type 1 matrix metalloproteinase) transcription by glomerular mesangial cellsInterleukin-21 receptor gene induction in human T cells is mediated by T-cell receptor-induced Sp1 activity.Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expressionAltered molecular response to adrenoreceptor-induced cardiac hypertrophy in Egr-1-deficient miceStat5b is essential for natural killer cell-mediated proliferation and cytolytic activityInferring time-varying network topologies from gene expression data.Cyclosporin A-sensitive transcription factor Egr-3 regulates Fas ligand expression.High-level expression of Egr-1 and Egr-1-inducible genes in mouse and human atherosclerosis.Early growth response-1 is required for CD154 transcription.Cigarette smoke-induced pulmonary inflammatory responses are mediated by EGR-1/GGPPS/MAPK signaling.The early growth response gene Egr2 (Alias Krox20) is a novel transcriptional target of transforming growth factor-β that is up-regulated in systemic sclerosis and mediates profibrotic responses.Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106aGGPPS, a new EGR-1 target gene, reactivates ERK 1/2 signaling through increasing Ras prenylation.Transgenic mice demonstrate novel promoter regions for tissue-specific expression of the urokinase receptor gene.Critical role for Rsk2 in T-lymphocyte activationOpposing regulation of T cell function by Egr-1/NAB2 and Egr-2/Egr-3.Dietary obesity-induced Egr-1 in adipocytes facilitates energy storage via suppression of FOXC2.Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapyp53CP, a putative p53 competing protein that specifically binds to the consensus p53 DNA binding sites: a third member of the p53 family?Egr-1 induces DARPP-32 expression in striatal medium spiny neurons via a conserved intragenic element.Induction of the interleukin-2/15 receptor beta-chain by the EWS-WT1 translocation product.Inhibition of the RelA(p65) NF-kappaB subunit by Egr-1.Egr-2 and Egr-3 are negative regulators of T cell activation.Transcription factors Sp1 and Sp3 alter vascular endothelial growth factor receptor expression through a novel recognition sequence.Early growth response protein-1 (Egr-1) is preferentially expressed in T helper type 2 (Th2) cells and is involved in acute transcription of the Th2 cytokine interleukin-4.Granulocyte colony-stimulating factor induces Egr-1 up-regulation through interaction of serum response element-binding proteins.Late expression of granulysin by microbicidal CD4+ T cells requires PI3K- and STAT5-dependent expression of IL-2Rbeta that is defective in HIV-infected patients.Snail associates with EGR-1 and SP-1 to upregulate transcriptional activation of p15INK4b.Oncogene-mediated downregulation of RECK, a novel transformation suppressor gene.Transcriptional regulation of the human nonmuscle myosin II heavy chain-A gene. Identification of three clustered cis-elements in intron-1 which modulate transcription in a cell type- and differentiation state-dependent manner.Angiotensin II induction of PDGF-C expression is mediated by AT1 receptor-dependent Egr-1 transactivation.Mouse Huntington's disease homolog mRNA levels: variation and allele effects.Phorbol Ester Activation of the Neuronal Nicotinic Acetylcholine Receptor α7 Subunit Gene
P2860
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P2860
The immediate-early gene product Egr-1 regulates the human interleukin-2 receptor beta-chain promoter through noncanonical Egr and Sp1 binding sites.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
The immediate-early gene produ ...... cal Egr and Sp1 binding sites.
@ast
The immediate-early gene produ ...... cal Egr and Sp1 binding sites.
@en
type
label
The immediate-early gene produ ...... cal Egr and Sp1 binding sites.
@ast
The immediate-early gene produ ...... cal Egr and Sp1 binding sites.
@en
prefLabel
The immediate-early gene produ ...... cal Egr and Sp1 binding sites.
@ast
The immediate-early gene produ ...... cal Egr and Sp1 binding sites.
@en
P2860
P356
P1476
The immediate-early gene produ ...... cal Egr and Sp1 binding sites.
@en
P2093
P2860
P304
P356
10.1128/MCB.17.7.3714
P407
P577
1997-07-01T00:00:00Z