about
Cysteine proteases as therapeutic targets: does selectivity matter? A systematic review of calpain and cathepsin inhibitorsMacrophage derived cystatin B/cathepsin B in HIV replication and neuropathogenesisNovel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compoundsCysteine protease inhibitors reduce brain beta-amyloid and beta-secretase activity in vivo and are potential Alzheimer's disease therapeuticsNitroxoline impairs tumor progression in vitro and in vivo by regulating cathepsin B activityThe anti-tumorigenic mushroom Agaricus blazei Murill enhances IL-1β production and activates the NLRP3 inflammasome in human macrophagesSynthesis and anticancer activity of carbosilane metallodendrimers based on arene ruthenium(ii) complexesDesign, synthesis and characterisation of new chimeric ruthenium(II)-gold(I) complexes as improved cytotoxic agents.In vitro and in vivo evaluation of water-soluble iminophosphorane ruthenium(II) compounds. A potential chemotherapeutic agent for triple negative breast cancerIdentification and characterization of 3-substituted pyrazolyl esters as alternate substrates for cathepsin B: the confounding effects of DTT and cysteine in biological assays.Evaluation of an orthogonal pooling strategy for rapid high-throughput screening of proteases.A double-headed cathepsin B inhibitor devoid of warhead.The identification, characterization and optimization of small molecule probes of cysteine proteases: experiences of the Penn Center for Molecular Discovery with cathepsin B and cathepsin L.How does heparin prevent the pH inactivation of cathepsin B? Allosteric mechanism elucidated by docking and molecular dynamicsTargeting MMP-9, uPAR, and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells.Cystatin C increases in cardiac injury: a role in extracellular matrix protein modulationDroplet electrospray ionization mass spectrometry for high throughput screening for enzyme inhibitorsInhibition of cysteine proteases in acute and chronic spinal cord injuryRNAi-mediated abrogation of cathepsin B and MMP-9 gene expression in a malignant meningioma cell line leads to decreased tumor growth, invasion and angiogenesis.Targeting Cathepsin B for Cancer Therapies.Expression profile of cathepsins indicates the potential of cathepsins B and D as prognostic factors in breast cancer patients.Cysteine cathepsin non-inhibitory binding partners: modulating intracellular trafficking and function.Cathepsin B as a potential prognostic and therapeutic marker for human lung squamous cell carcinoma.The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation.Do antidiabetic medications play a specific role in differentiated thyroid cancer compared to other cancer types?Microbial and fungal protease inhibitors--current and potential applications.Influence of the π-coordinated arene on the anticancer activity of ruthenium(II) carbohydrate organometallic complexesMicrobial inhibitors of cysteine proteases.Cathepsin-B induced controlled release from peptide-capped mesoporous silica nanoparticles.Cathepsin B Inhibitors: Combining Dipeptide Nitriles with an Occluding Loop Recognition Element by Click Chemistry.Smart dual-functional warhead for folate receptor-specific activatable imaging and photodynamic therapy.Silver and Gold Nanoparticles Alter Cathepsin Activity In vitro.The lysosome among targets of metformin: new anti-inflammatory uses for an old drug?Insulin-like growth factor II receptor-mediated intracellular retention of cathepsin B is essential for transformation of endothelial cells by Kaposi's sarcoma-associated herpesvirus.Cathepsins in heart disease-chewing on the heartache?Cerebrospinal fluid cathepsin B and S.Elevated serum cathepsin B concentration in pregnant women is associated with preeclampsia.Design, characterization and cellular uptake studies of fluorescence-labeled prototypic cathepsin inhibitors.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Inhibitors of cathepsin B.
@ast
Inhibitors of cathepsin B.
@en
type
label
Inhibitors of cathepsin B.
@ast
Inhibitors of cathepsin B.
@en
prefLabel
Inhibitors of cathepsin B.
@ast
Inhibitors of cathepsin B.
@en
P1476
Inhibitors of cathepsin B
@en
P2093
P304
P356
10.2174/092986706777935122
P577
2006-01-01T00:00:00Z