Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene.
about
Transducin-like enhancer of split proteins, the human homologs of Drosophila groucho, interact with hepatic nuclear factor 3betaLoss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancerExendin-4 differentiation of a human pancreatic duct cell line into endocrine cells: involvement of PDX-1 and HNF3beta transcription factorsConserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6Diabetes outfoxed by GLP-1?Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expressionConnective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesisMechanisms of action of glucagon-like peptide 1 in the pancreasPancreatic regulation of glucose homeostasisGenetically engineered mouse models of pancreatic adenocarcinomaRedox homeostasis in pancreatic β cellsExtended exenatide administration enhances lipid metabolism and exacerbates pancreatic injury in mice on a high fat, high carbohydrate dietTranscription factor regulation of pancreatic organogenesis, differentiation and maturationAutoregulation and maturity onset diabetes of the young transcription factors control the human PAX4 promoterpdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasisThe forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growthMembers of the large Maf transcription family regulate insulin gene transcription in islet beta cellsActivin receptor patterning of foregut organogenesisFoxa2 (HNF3beta ) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin releasePDX:PBX complexes are required for normal proliferation of pancreatic cells during developmentTranscription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.Network insights into the genes regulated by hepatocyte nuclear factor 4 in response to drug induced perturbations: a reviewPdx1 is post-translationally modified in vivo and serine 61 is the principal site of phosphorylationFoxa3 (HNF-3gamma) binds to and activates the rat proglucagon gene promoter but is not essential for proglucagon gene expressionEpigenomic plasticity enables human pancreatic α to β cell reprogramming.An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2).Activation of PyMT in beta cells induces irreversible hyperplasia, but oncogene-dependent acinar cell carcinomas when activated in pancreatic progenitors.Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during developmentDown-regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5: a novel mechanism for inhibition of cellular proliferation and insulin secretion by somatostatin.Dissecting the transcriptional network of pancreatic islets during development and differentiation.A recombinase-mediated cassette exchange-derived cyan fluorescent protein reporter allele for Pdx1.Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3betaExperimental control of pancreatic development and maintenance.Gene regulatory factors in pancreatic development.Human bone marrow mesenchymal stem cells can express insulin and key transcription factors of the endocrine pancreas developmental pathway upon genetic and/or microenvironmental manipulation in vitro.Metabolic programming: causes and consequences.Forkhead box protein A2 (FOXA2) protein stability and activity are regulated by sumoylation.Two tales of antioxidant enzymes on β cells and diabetes.Historical perspective: beginnings of the beta-cell: current perspectives in beta-cell development
P2860
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P2860
Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Hepatocyte nuclear factor 3bet ...... anscription of the pdx-1 gene.
@ast
Hepatocyte nuclear factor 3bet ...... anscription of the pdx-1 gene.
@en
type
label
Hepatocyte nuclear factor 3bet ...... anscription of the pdx-1 gene.
@ast
Hepatocyte nuclear factor 3bet ...... anscription of the pdx-1 gene.
@en
prefLabel
Hepatocyte nuclear factor 3bet ...... anscription of the pdx-1 gene.
@ast
Hepatocyte nuclear factor 3bet ...... anscription of the pdx-1 gene.
@en
P2093
P2860
P356
P1476
Hepatocyte nuclear factor 3bet ...... anscription of the pdx-1 gene.
@en
P2093
C V Wright
E Henderson
M F Offield
M Peshavaria
P2860
P304
P356
10.1128/MCB.17.10.6002
P407
P577
1997-10-01T00:00:00Z