The common fragile site FRA16D and its associated gene WWOX are highly conserved in the mouse at Fra8E1 - Wikidata - awgldk - TriplyDB

The common fragile site FRA16D and its associated gene WWOX are highly conserved in the mouse at Fra8E1

The common fragile site FRA16D and its associated gene WWOX are highly conserved in the mouse at Fra8E1

http://www.wikidata.org/entity/Q28215998

about

sameAs

Molecular basis for expression of common and rare fragile sites Targeted deletion of Wwox reveals a tumor suppressor function Plasticity of DNA replication initiation in Epstein-Barr virus episomes Pleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer Cells WWOX, the common chromosomal fragile site, FRA16D, cancer gene WWOX hypomorphic mice display a higher incidence of B-cell lymphomas and develop testicular atrophy.Association between decreased WWOX protein expression and thyroid cancer development WWOX at the crossroads of cancer, metabolic syndrome related traits and CNS pathologies.One in four individuals of African-American ancestry harbors a 5.5kb deletion at chromosome 11q13.1.Conditional Wwox deletion in mouse mammary gland by means of two Cre recombinase approaches.Common fragile site tumor suppressor genes and corresponding mouse models of cancer.Common chromosome fragile sites in human and murine epithelial cells and FHIT/FRA3B loss-induced global genome instability Common fragile sites are conserved features of human and mouse chromosomes and relate to large active genes.WW domain-containing oxidoreductase in neuronal injury and neurological diseases.Increased common fragile site expression, cell proliferation defects, and apoptosis following conditional inactivation of mouse Hus1 in primary cultured cells.Requirement of evading apoptosis for HIF-1α-induced malignant progression in mouse cells.A genome-wide analysis of common fragile sites: what features determine chromosomal instability in the human genome?Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells.Defining ATM-Independent Functions of the Mre11 Complex with a Novel Mouse Model WWOX in biological control and tumorigenesis.The JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX.Introduction to a thematic issue for WWOX.WWOX gene and gene product: tumor suppression through specific protein interactions.Role of the WWOX tumor suppressor gene in bone homeostasis and the pathogenesis of osteosarcoma.Interplay between genetic and epigenetic factors governs common fragile site instability in cancer.Very large common fragile site genes and their potential role in cancer development.WWOX: a fragile tumor suppressor.WWOX, large common fragile site genes, and cancer.The "enemies within": regions of the genome that are inherently difficult to replicate.A high resolution map of mammalian X chromosome fragile regions assessed by large-scale comparative genomics.Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability.PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome.Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair.Characterization of a conserved aphidicolin-sensitive common fragile site at human 4q22 and mouse 6C1: possible association with an inherited disease and cancer.RORA, a large common fragile site gene, is involved in cellular stress response.The long non-coding RNA PARTICLE is associated with WWOX and the absence of FRA16D breakage in osteosarcoma patients.Common chromosomal fragile site FRA16D tumor suppressor WWOX gene expression and metabolic reprograming in cells.Modeling WWOX Loss of Function : What Have We Learned?

P2860

Q24653358-FBCCCEB1-4F07-43D3-8FFB-AAA738FDF82D Q24681190-AB56D56A-78E2-4FB9-987D-DC1C1C0A5658 Q24793031-B4D0186A-6DC5-48E2-8F6C-AAC4B415AE90 Q28080922-0F662DA0-8F95-4268-8E62-7F4BA2B719A9 Q28207184-5D8FDD6F-C751-4155-AD67-6AC86CB0E1FC Q34083683-751FD713-8215-4CBC-A3B5-29FA931C8180 Q34114283-87E17BF9-EE91-4389-A1D2-22EB76B5E7A9 Q34120466-B0AD57C7-25F3-4A36-B67A-EF8DFD9CC0BB Q34171243-634E8C80-2196-4CCA-87AC-980A814E4739 Q34264825-44F415C3-CC7B-40B2-B722-277589B6076E Q34557827-942569DC-430F-4071-9D3E-95362C7DF448 Q34940529-9CEE3EA8-46F6-4584-A7F3-060DE0483C20 Q35056705-87464A0E-0C5A-4C51-A3D0-B4F2FF74AE64 Q35067919-8D2EDFD2-1861-4ABE-86C4-BFA21B0F7576 Q35650781-385F0B1D-2D59-4B67-8F98-F56D9BF03022 Q35878522-CE1ABEE2-C13D-49B8-93ED-5348C4AB586D Q36021725-F3AEC155-B0FF-4BC3-812F-EE733D039A0D Q36577607-84C0FD6D-0105-47B6-B2C5-0A21A41D7EF9 Q36586039-8DFEC174-FD86-4C68-8716-F2FEEC58EB8F Q36801619-77FFA885-5256-428D-885A-6B4632DB8C45 Q36953585-8C6CE995-F805-4EE1-A056-47C3BD3DFECD Q37071036-6EA72F1E-1FAE-4010-9B68-3BCE9D32C323 Q37690302-1B04414E-BF75-449E-85DB-AD0805E8CC5A Q37897986-286CB596-48A3-46D5-974D-05CD282EB093 Q38258279-BB81BC4E-0A18-4171-9953-9D3F84C7A5DD Q38258543-6ABC0E83-6656-4FDE-951F-2C7EA92676D7 Q38299692-8F6948F2-C7CB-495E-BB64-3B6DC9F0F541 Q38321093-9D5A9A80-D6F2-421E-9CE7-D2FE7C595386 Q38723121-262C711E-95D4-4F98-A8E1-06A657BC0A2D Q39149580-94A7FBD8-D97C-451E-950B-D9EF5C48F33C Q39705486-9F60A0A0-E2C0-4846-9FC9-1C6CD8886141 Q41223344-0D92DCF4-1AF3-440C-9670-16D86CEC39B0 Q42700921-27BC0DC1-DF43-4993-A969-547D9284A97E Q45001863-361EC7E0-9A24-450F-8797-C396429E699F Q46931410-BF10CC88-4978-432A-AAB8-4D2A70B73EA2 Q47103604-631B251A-20FC-4EC3-8434-3FA4E2376772 Q50908933-EFBDE40D-1BFA-4A17-98AB-E41DE4661E49 Q58123045-BF80B4DB-7FBF-4FC8-BDC7-1E14B63525AD

P2860

The common fragile site FRA16D and its associated gene WWOX are highly conserved in the mouse at Fra8E1

http://www.wikidata.org/entity/Q28215998

description

2002 nî lūn-bûn

@nan

2002 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

The common fragile site FRA16D ...... nserved in the mouse at Fra8E1

@ast

The common fragile site FRA16D ...... nserved in the mouse at Fra8E1

@en

The common fragile site FRA16D ...... nserved in the mouse at Fra8E1

@nl

type

label

The common fragile site FRA16D ...... nserved in the mouse at Fra8E1

@ast

The common fragile site FRA16D ...... nserved in the mouse at Fra8E1

@en

The common fragile site FRA16D ...... nserved in the mouse at Fra8E1

@nl

prefLabel

The common fragile site FRA16D ...... nserved in the mouse at Fra8E1

@ast

The common fragile site FRA16D ...... nserved in the mouse at Fra8E1

@en

The common fragile site FRA16D ...... nserved in the mouse at Fra8E1

@nl

P1433

Q28215998-A75E891B-82A1-45A3-BD06-F14B76F95BA5

P1476

Q28215998-8C91C70B-9465-4496-9664-BBC857E70E2B

P2093

Q28215998-16592FF6-A182-4D52-9C8A-6E86F662B59E

Q28215998-73E4F3A2-1878-47E2-913E-D19BF2C4DA96

Q28215998-843FDB37-F357-41ED-A63F-D991150A9529

Q28215998-A04D8928-12A7-464B-A6A2-7C2A939E0FB8

Q28215998-D03A4513-9587-420E-8BAE-2FF0CE6D9C83

P2860

Q28215998-0A6064F0-18B1-4F02-B95D-275E4755D6B6

Q28215998-0B7F16BF-989A-4C1A-A11E-FF14D01F30C4

Q28215998-0F7E0C09-E0B0-4AC3-8E88-3E9A74C6F6F8

Q28215998-13D932DA-EE42-48F9-B1D0-30E04535AB8F

Q28215998-155EEDFE-0684-45D5-ABB1-B86BE57015E7

Q28215998-31E23154-410B-462B-8370-6F3B3B394536

Q28215998-36AC2E87-E8FC-46B5-AD6C-45791A3DF057

Q28215998-4029D5AF-52A7-476B-9D8B-5B8863D64366

Q28215998-449AE73B-44F7-4321-8266-40F484662156

Q28215998-4FE66987-7B0B-4C98-8D9A-3B1BF7A12EBA

P304

Q28215998-D4A16A71-9107-472B-A178-67A45105C605

P31

Q28215998-98884B0A-E710-43C7-8AED-D4332BC6D8BB

P356

Q28215998-84041C15-7AE2-4136-A5CC-17F5FE771C03

P407

Q28215998-5D530C73-23D9-4A16-862B-4A644C37B905

P433

Q28215998-19477AB6-A19F-4C93-A98A-AC5553C08196

P478

Q28215998-BAF0E16C-B040-4148-9245-2F4FACD7237B

P577

Q28215998-E62302CC-6E83-4E98-A5E1-F0F8E10AEDD3

P698

Q28215998-99FA8CBA-DA4A-4585-9D09-E5C2823A8E74

P356

P1433

Genes, Chromosomes and Cancer

P1476

The common fragile site FRA16D ...... nserved in the mouse at Fra8E1

@en

P2093

David I Smith

http://www.w3.org/2001/XMLSchema#string

Eric Calhoun

http://www.w3.org/2001/XMLSchema#string

Kurt A Krummel

http://www.w3.org/2001/XMLSchema#string

Leslie A Phillips

http://www.w3.org/2001/XMLSchema#string

Stacy R Denison

http://www.w3.org/2001/XMLSchema#string

P2860

Initial sequencing and analysis of the human genome

The Sequence of the Human Genome

Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells

Genomic sequencing

Evolutionary analyses of the human genome

Construction and characterization of a human bacterial artificial chromosome library

Association of a chromosome deletion syndrome with a fragile site within the proto-oncogene CBL2

PipMaker--a web server for aligning two genomic DNA sequences

Interspersed repeats and other mementos of transposable elements in mammalian genomes

Translocation breakpoints in FHIT and FRA3B in both homologs of chromosome 3 in an esophageal adenocarcinoma.

P304

154-67

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/GCC.10047

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

34

http://www.w3.org/2001/XMLSchema#string

P577

2002-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

11979549

http://www.w3.org/2001/XMLSchema#string