Cell surface expression of the Alzheimer disease-related presenilin proteins.
about
A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 proteinThe novel presenilin-1-associated protein is a proapoptotic mitochondrial proteinInteraction of Alzheimer's presenilin-1 and presenilin-2 with Bcl-X(L). A potential role in modulating the threshold of cell deathMice lacking both presenilin genes exhibit early embryonic patterning defectsPeptides of presenilin-1 bind the amyloid precursor protein ectodomain and offer a novel and specific therapeutic approach to reduce ß-amyloid in Alzheimer's diseasePresenilin-1, nicastrin, amyloid precursor protein, and gamma-secretase activity are co-localized in the lysosomal membraneEndogenous presenilin 1 redistributes to the surface of lamellipodia upon adhesion of Jurkat cells to a collagen matrix.Alzheimer's disease-associated presenilin 2 interacts with DRAL, an LIM-domain protein.The role of cell cycle-mediated events in Alzheimer's disease.The seven-transmembrane spanning topography of the Alzheimer disease-related presenilin proteins in the plasma membranes of cultured cells.On the spurious endoproteolytic processing of the presenilin proteins in cultured cells and tissues.Benchmarking B-cell epitope prediction for the design of peptide-based vaccines: problems and prospects.Neurons bearing presenilins: weapons for defense or suicide?The presenilins turned inside out: implications for their structures and functions.Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation.Additional evidence for an eight-transmembrane-domain topology for Caenorhabditis elegans and human presenilins.Review: cell cycle aberrations and neurodegeneration.Gamma-secretase activity of presenilin 1 regulates acetylcholine muscarinic receptor-mediated signal transduction.The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein.Presenilin 1 controls gamma-secretase processing of amyloid precursor protein in pre-golgi compartments of hippocampal neuronsAssociation between presenilin-1 polymorphism and maternal meiosis II errors in Down syndrome.
P2860
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P2860
Cell surface expression of the Alzheimer disease-related presenilin proteins.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Cell surface expression of the Alzheimer disease-related presenilin proteins.
@ast
Cell surface expression of the Alzheimer disease-related presenilin proteins.
@en
type
label
Cell surface expression of the Alzheimer disease-related presenilin proteins.
@ast
Cell surface expression of the Alzheimer disease-related presenilin proteins.
@en
prefLabel
Cell surface expression of the Alzheimer disease-related presenilin proteins.
@ast
Cell surface expression of the Alzheimer disease-related presenilin proteins.
@en
P2860
P356
P1476
Cell surface expression of the Alzheimer disease-related presenilin proteins.
@en
P2093
P2860
P304
P356
10.1073/PNAS.94.18.9926
P407
P577
1997-09-01T00:00:00Z