Interaction of Alzheimer's presenilin-1 and presenilin-2 with Bcl-X(L). A potential role in modulating the threshold of cell death
about
Presenilin 2 interacts with sorcin, a modulator of the ryanodine receptorAATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4The novel presenilin-1-associated protein is a proapoptotic mitochondrial proteinSiah-1 binds and regulates the function of NumbTwo isoforms of PSAP/MTCH1 share two proapoptotic domains and multiple internal signals for import into the mitochondrial outer membraneForebrain degeneration and ventricle enlargement caused by double knockout of Alzheimer's presenilin-1 and presenilin-2Alzheimer's disease-associated presenilin 2 interacts with DRAL, an LIM-domain protein.LDL receptor-related protein (LRP) in Alzheimer's disease: towards a unified theory of pathogenesis.CD47 and the 19 kDa interacting protein-3 (BNIP3) in T cell apoptosis.Mitochondrial and Cell Death Mechanisms in Neurodegenerative Diseases.Neurons bearing presenilins: weapons for defense or suicide?Pathological and physiological functions of presenilins.The mitochondrial death pathway: a promising therapeutic target in diseasesEffect of presenilins in the apoptosis of thymocytes and homeostasis of CD8+ T cellsOxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor proteinThe role of presenilin and its interacting proteins in the biogenesis of Alzheimer's beta amyloidPresenilin: RIP and beyond.Presenilin 2 overexpression is associated with apoptosis in Neuro2a cells.Regulation of anti-apoptotic BCL2-proteins by non-canonical interactions: the next step forward or two steps back?Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling.Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53.Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and NeurodegenerationCaspase cleavage of exon 9 deleted presenilin-1 is an early event in apoptosis induced by calcium ionophore A 23187 in SH-SY5Y neuroblastoma cells.Akt activity in presenilin 1 wild-type and mutation transfected human SH-SY5Y neuroblastoma cells after serum deprivation and high glucose stress.The C-terminal fragment of presenilin 2 triggers p53-mediated staurosporine-induced apoptosis, a function independent of the presenilinase-derived N-terminal counterpart.Zebrafish lacking Alzheimer presenilin enhancer 2 (Pen-2) demonstrate excessive p53-dependent apoptosis and neuronal loss.
P2860
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P2860
Interaction of Alzheimer's presenilin-1 and presenilin-2 with Bcl-X(L). A potential role in modulating the threshold of cell death
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Interaction of Alzheimer's pre ...... ng the threshold of cell death
@ast
Interaction of Alzheimer's pre ...... ng the threshold of cell death
@en
Interaction of Alzheimer's pre ...... ng the threshold of cell death
@nl
type
label
Interaction of Alzheimer's pre ...... ng the threshold of cell death
@ast
Interaction of Alzheimer's pre ...... ng the threshold of cell death
@en
Interaction of Alzheimer's pre ...... ng the threshold of cell death
@nl
prefLabel
Interaction of Alzheimer's pre ...... ng the threshold of cell death
@ast
Interaction of Alzheimer's pre ...... ng the threshold of cell death
@en
Interaction of Alzheimer's pre ...... ng the threshold of cell death
@nl
P2093
P2860
P3181
P356
P1476
Interaction of Alzheimer's pre ...... ng the threshold of cell death
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.274.34.24007
P407
P577
1999-08-20T00:00:00Z