Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma.

about

Combined analysis of gene expression and genome binding profiles identified potential therapeutic targets of ciclopirox in Ewing sarcoma.HNRNPH1 is required for rhabdomyosarcoma cell growth and survival.

P2860

Q50067605-9DC5D2E9-4E55-4E36-81C1-DD92C7E6FA07 Q51758996-6EAB454B-AC53-457D-9C73-75CCA716DBD8

P2860

Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma.

Item

http://www.wikidata.org/entity/Q36584775

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Functional Genomic Screening R ...... ulnerability in Ewing Sarcoma.

@ast

Functional Genomic Screening R ...... ulnerability in Ewing Sarcoma.

@en

type

Item

label

Functional Genomic Screening R ...... ulnerability in Ewing Sarcoma.

@ast

Functional Genomic Screening R ...... ulnerability in Ewing Sarcoma.

@en

prefLabel

Functional Genomic Screening R ...... ulnerability in Ewing Sarcoma.

@ast

Functional Genomic Screening R ...... ulnerability in Ewing Sarcoma.

@en

P1476

Functional Genomic Screening R ...... ulnerability in Ewing Sarcoma.

@en

P2093

Carleen A Klumpp-Thomas

http://www.w3.org/2001/XMLSchema#string

Eugen Buehler

http://www.w3.org/2001/XMLSchema#string

Guillermo O Rangel Rivera

http://www.w3.org/2001/XMLSchema#string

Jack Zhu

http://www.w3.org/2001/XMLSchema#string

Konrad Huppi

http://www.w3.org/2001/XMLSchema#string

Kristen Gehlhaus

http://www.w3.org/2001/XMLSchema#string

Lee J Helman

http://www.w3.org/2001/XMLSchema#string

Magdalena Grandin

http://www.w3.org/2001/XMLSchema#string

Matt L Harlow

http://www.w3.org/2001/XMLSchema#string

Maura O'Neill

http://www.w3.org/2001/XMLSchema#string

P2860

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1

Chromosome translocation based on illegitimate recombination in human tumors

The genomic landscape of pediatric Ewing sarcoma.

Median absolute deviation to improve hit selection for genome-scale RNAi screens.

The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation.

Common seed analysis to identify off-target effects in siRNA screens.

Determination of the RNA binding specificity of the heterogeneous nuclear ribonucleoprotein (hnRNP) H/H'/F/2H9 family.

The anti-tumor drug E7107 reveals an essential role for SF3b in remodeling U2 snRNP to expose the branch point-binding region.

Phase I pharmacokinetic and pharmacodynamic study of the first-in-class spliceosome inhibitor E7107 in patients with advanced solid tumors.

P304

598-610

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.CELREP.2015.12.063

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Natasha J. Caplen

Nirmalya Sen

P577

2016-01-13T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

290622573

http://www.w3.org/2001/XMLSchema#string

P698

26776507

http://www.w3.org/2001/XMLSchema#string

P932

4755295

http://www.w3.org/2001/XMLSchema#string

Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma.

about

P2860

P2860

Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932