FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver
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Metabolism Disrupting Chemicals and Metabolic DisordersThe Sweet Path to Metabolic Demise: Fructose and Lipid SynthesisKLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference.FGF21 resistance is not mediated by downregulation of beta-klotho expression in white adipose tissueHepatic, adipocyte, enteric and pancreatic hormones: response to dietary macronutrient composition and relationship with metabolism.The significance of beige and brown fat in humans.Hepatic Aryl Hydrocarbon Receptor Attenuates Fibroblast Growth Factor 21 ExpressionRoux-en-Y gastric bypass surgery is effective in fibroblast growth factor-21 deficient mice.Circulating FGF21 in humans is potently induced by short term overfeeding of carbohydratesA critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism.Fibroblast growth factor 21, assisted by elevated glucose, activates paraventricular nucleus NUCB2/Nesfatin-1 neurons to produce satiety under fed states.On the Run for Hippocampal Plasticity.Fibroblast growth factor 21: a regulator of metabolic disease and health span.FGF21 Regulates Metabolism Through Adipose-Dependent and -Independent Mechanisms.Fgf21 regulates T-cell development in the neonatal and juvenile thymus.Macronutrient Intake-Associated FGF21 Genotype Modifies Effects of Weight-Loss Diets on 2-Year Changes of Central Adiposity and Body Composition: The POUNDS Lost Trial.The Role of Carbohydrate Response Element Binding Protein in Intestinal and Hepatic Fructose Metabolism.The regulation and role of carbohydrate response element binding protein in metabolic homeostasis and disease.Low protein-induced increases in FGF21 drive UCP1-dependent metabolic but not thermoregulatory endpoints.Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine.A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response.Neural and Molecular Mechanisms Involved in Controlling the Quality of Feeding Behavior: Diet Selection and Feeding Patterns.Dietary manipulations that induce ketosis activate the HPA axis in male rats and mice: a potential role for fibroblast growth factor-21.FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes.Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice.Hepatic Crtc2 controls whole body energy metabolism via a miR-34a-Fgf21 axis.A low-protein diet induces body weight loss and browning of subcutaneous white adipose tissue through enhanced expression of hepatic fibroblast growth factor 21 (FGF21).Intestinal, but not hepatic, ChREBP is required for fructose tolerance.Fibroblast growth factor 21 increases hepatic oxidative capacity but not physical activity or energy expenditure in hepatic peroxisome proliferator-activated receptor γ coactivator-1α-deficient mice.Roux-en-Y Gastric Bypass Surgery Has Unique Effects on Postprandial FGF21 but Not FGF19 Secretion.FGF21 Is an Insulin-Dependent Postprandial Hormone in Adult Humans.FGF21 and metabolic disease in 2016: A new frontier in FGF21 biology.Fructose metabolism and metabolic disease.Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes.Behavioral tracing demonstrates dietary nutrient discrimination in two-spotted crickets Gryllus bimaculatus.ChREBP refines the hepatic response to fructose to protect the liver from injury.Increased glucose-stimulated FGF21 response to oral glucose in obese nondiabetic subjects after Roux-en-Y gastric bypass.The biology of glucagon and the consequences of hyperglucagonemia.A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure.FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at Oktoberfest.
P2860
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P2860
FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
FGF21 Mediates Endocrine Contr ...... Taste Preference by the Liver
@ast
FGF21 Mediates Endocrine Contr ...... Taste Preference by the Liver
@en
type
label
FGF21 Mediates Endocrine Contr ...... Taste Preference by the Liver
@ast
FGF21 Mediates Endocrine Contr ...... Taste Preference by the Liver
@en
prefLabel
FGF21 Mediates Endocrine Contr ...... Taste Preference by the Liver
@ast
FGF21 Mediates Endocrine Contr ...... Taste Preference by the Liver
@en
P2093
P2860
P50
P1433
P1476
FGF21 Mediates Endocrine Contr ...... Taste Preference by the Liver
@en
P2093
Adriana Ibarra Urizar
Andreas N Madsen
Andrew A Pieper
Anthony P Thompson
Aurelie Vandenbeuch
Catherine B Anderson
Kristin E Claflin
Lila Peltekian
Lucas D BonDurant
Martin D Cassell
P2860
P304
P356
10.1016/J.CMET.2015.12.003
P50
P577
2015-12-22T00:00:00Z