Role of the acidic N' region of cardiac troponin I in regulating myocardial function.
about
TNNI3K is a novel mediator of myofilament function and phosphorylates cardiac troponin IIntegration of troponin I phosphorylation with cardiac regulatory networksCell biology of sarcomeric protein engineering: disease modeling and therapeutic potentialThe heart-specific NH2-terminal extension regulates the molecular conformation and function of cardiac troponin INew insights into the functional significance of the acidic region of the unique N-terminal extension of cardiac troponin IStructural basis for the in situ Ca(2+) sensitization of cardiac troponin C by positive feedback from force-generating myosin cross-bridgesRemoval of the cardiac troponin I N-terminal extension improves cardiac function in aged mice.Phosphorylation of cardiac troponin I at protein kinase C site threonine 144 depresses cooperative activation of thin filaments.Computational studies of the effect of the S23D/S24D troponin I mutation on cardiac troponin structural dynamics.Signaling and myosin-binding protein C.Protein phosphorylation and signal transduction in cardiac thin filaments.Effects of HCM cTnI mutation R145G on troponin structure and modulation by PKA phosphorylation elucidated by molecular dynamics simulationsTargeted Next-Generation Sequencing Reveals Hot Spots and Doubly Heterozygous Mutations in Chinese Patients with Familial CardiomyopathyTroponin I Mutations R146G and R21C Alter Cardiac Troponin Function, Contractile Properties, and Modulation by Protein Kinase A (PKA)-mediated Phosphorylation.Significance of troponin dynamics for Ca2+-mediated regulation of contraction and inherited cardiomyopathy.Effect of N-Terminal Extension of Cardiac Troponin I on the Ca(2+) Regulation of ATP Binding and ADP Dissociation of Myosin II in Native Cardiac Myofibrils.Cardiac troponin structure-function and the influence of hypertrophic cardiomyopathy associated mutations on modulation of contractility.Cardiac troponin I tyrosine 26 phosphorylation decreases myofilament Ca2+ sensitivity and accelerates deactivation.N-terminal phosphorylation of cardiac troponin-I reduces length-dependent calcium sensitivity of contraction in cardiac muscle.
P2860
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P2860
Role of the acidic N' region of cardiac troponin I in regulating myocardial function.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Role of the acidic N' region of cardiac troponin I in regulating myocardial function.
@ast
Role of the acidic N' region of cardiac troponin I in regulating myocardial function.
@en
type
label
Role of the acidic N' region of cardiac troponin I in regulating myocardial function.
@ast
Role of the acidic N' region of cardiac troponin I in regulating myocardial function.
@en
prefLabel
Role of the acidic N' region of cardiac troponin I in regulating myocardial function.
@ast
Role of the acidic N' region of cardiac troponin I in regulating myocardial function.
@en
P2093
P2860
P356
P1433
P1476
Role of the acidic N' region of cardiac troponin I in regulating myocardial function.
@en
P2093
Hanna Osinska
Jack W Howarth
Jeffrey Robbins
John N Lorenz
Natosha Finley
Paul R Rosevear
Raisa Klevitsky
Sakthivel Sadayappan
P2860
P304
P356
10.1096/FJ.07-9458COM
P407
P577
2007-11-05T00:00:00Z