Antisense inhibition of the p65 subunit of NF-kappa B blocks tumorigenicity and causes tumor regression
about
Human CPR (cell cycle progression restoration) genes impart a Far- phenotype on yeast cells.Rel/Nuclear factor-kappa B apoptosis pathways in human cervical cancer cells.Inhibition of dengue virus by novel, modified antisense oligonucleotidesAntisense oligonucleotide inhibition of hepatitis C virus (HCV) gene expression in livers of mice infected with an HCV-vaccinia virus recombinantEstrogen withdrawal-induced NF-kappaB activity and bcl-3 expression in breast cancer cells: roles in growth and hormone independenceSignal-induced degradation of I(kappa)B(alpha): association with NF-kappaB and the PEST sequence in I(kappa)B(alpha) are not requiredIdentification of a negative regulatory cis-element in the enhancer core region of the prostate-specific antigen promoter: implications for intersection of androgen receptor and nuclear factor-kappaB signalling in prostate cancer cells.zeta PKC induces phosphorylation and inactivation of I kappa B-alpha in vitro.Reactive oxygen species from NAD(P)H:quinone oxidoreductase constitutively activate NF-kappaB in malignant melanoma cells.Correlation of NF-kappaB signal pathway with tumor metastasis of human head and neck squamous cell carcinoma.Differentiation of immortal cells inhibits telomerase activity.Activation of p73 and induction of Noxa by DNA damage requires NF-kappa B.Reduced expression of beta-catenin inhibitor Chibby in colon carcinoma cell lines.Identification of gene function and functional pathways by systemic plasmid-based ribozyme targeting in adult miceIrreversible EGFR inhibitor EKB-569 targets low-LET γ-radiation-triggered rel orchestration and potentiates cell death in squamous cell carcinoma.An NAD(P)H oxidase regulates growth and transcription in melanoma cells.Glycogen synthase kinase-3β, NF-κB signaling, and tumorigenesis of human osteosarcoma.5'-Cholesteryl-phosphorothioate oligodeoxynucleotides: potent inhibition of methotrexate transport and antagonism of methotrexate toxicity in cells containing the reduced-folate carrier.Inhibition of NF-kappa B-Rel A expression by antisense oligodeoxynucleotides suppresses synthesis of urokinase-type plasminogen activator (uPA) but not its inhibitor PAI-1.Nf-kappa B, chemokine gene transcription and tumour growthNF-kappaB and cancer: how intimate is this relationshipSequence-independent induction of Sp1 transcription factor activity by phosphorothioate oligodeoxynucleotidesAntisense oligonucleotides adsorbed to polyalkylcyanoacrylate nanoparticles specifically inhibit mutated Ha-ras-mediated cell proliferation and tumorigenicity in nude mice.Identification and characterization of a cell membrane nucleic acid channel.Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotidesGenome-wide RNAi screening identifies TMIGD3 isoform1 as a suppressor of NF-κB and osteosarcoma progressionThiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B.Leukemia treatment in severe combined immunodeficiency mice by antisense oligodeoxynucleotides targeting cooperating oncogenesOligodeoxynucleotides enhance lipopolysaccharide-stimulated synthesis of tumor necrosis factor: dependence on phosphorothioate modification and reversal by heparin.v-rel Induces ectopic expression of an adhesion molecule, DM-GRASP, during B-lymphoma developmentConstitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth.relA over-expression reduces tumorigenicity and activates apoptosis in human cancer cells.Molecular basis of 'hypoxic' breast cancer cell radio-sensitization: phytochemicals converge on radiation induced Rel signaling.IkappaB is a substrate for a selective pathway of lysosomal proteolysis.Nuclear factor-kappa B activation by the CXC chemokine melanoma growth-stimulatory activity/growth-regulated protein involves the MEKK1/p38 mitogen-activated protein kinase pathwayMolecular approaches to sarcoma therapy.NF-kappaB as a prognostic marker and therapeutic target in chronic lymphocytic leukemia.E3 ubiquitin ligase Pirh2 enhances tumorigenic properties of human non-small cell lung carcinoma cells.NF-kappaB DNA-binding activity after high peak power pulsed microwave (8.2 GHz) exposure of normal human monocytes.Sequence context of antisense RelA/NF-kappa B phosphorothioates determines specificity.
P2860
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P2860
Antisense inhibition of the p65 subunit of NF-kappa B blocks tumorigenicity and causes tumor regression
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Antisense inhibition of the p6 ...... ty and causes tumor regression
@ast
Antisense inhibition of the p6 ...... ty and causes tumor regression
@en
type
label
Antisense inhibition of the p6 ...... ty and causes tumor regression
@ast
Antisense inhibition of the p6 ...... ty and causes tumor regression
@en
prefLabel
Antisense inhibition of the p6 ...... ty and causes tumor regression
@ast
Antisense inhibition of the p6 ...... ty and causes tumor regression
@en
P2093
P2860
P356
P1476
Antisense inhibition of the p6 ...... ty and causes tumor regression
@en
P2093
K A Higgins
K Dorshkind
T A Coleman
U M Sarmiento
W A McComas
P2860
P304
P356
10.1073/PNAS.90.21.9901
P407
P50
P577
1993-11-01T00:00:00Z