Glycosyl-phosphatidylinositol-anchored or integral membrane forms of CD14 mediate identical cellular responses to endotoxin
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The specificity for the differentiation blocking activity of carcinoembryonic antigen resides in its glycophosphatidyl-inositol anchorLipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2A GPI-linked protein that interacts with Ret to form a candidate neurturin receptorCD14 is a cell-activating receptor for bacterial peptidoglycanBMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2CBacterial lipopolysaccharide inhibits dengue virus infection of primary human monocytes/macrophages by blockade of virus entry via a CD14-dependent mechanism.Differential responses of human mononuclear phagocytes to mycobacterial lipoarabinomannans: role of CD14 and the mannose receptorCell activation mediated by glycosylphosphatidylinositol-anchored or transmembrane forms of CD14.CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognitionFluorescence resonance energy transfer analysis of lipopolysaccharide in detergent micellesThe bacterial endotoxin lipopolysaccharide has the ability to target the brain in upregulating its membrane CD14 receptor within specific cellular populations.Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock.Stimulation of the ceramide pathway partially mimics lipopolysaccharide-induced responses in murine peritoneal macrophages.Modulating LPS signal transduction at the LPS receptor complex with synthetic Lipid A analoguesCD14 and toll-like receptor 4: a link between infection and acute coronary events?Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events.Lipopolysaccharide (LPS)-induced macrophage activation and signal transduction in the absence of Src-family kinases Hck, Fgr, and LynSolution NMR studies provide structural basis for endotoxin pattern recognition by the innate immune receptor CD14.Glycosyl-phosphatidylinositol-anchored and transmembrane forms of CD46 display similar measles virus receptor properties: virus binding, fusion, and replication; down-regulation by hemagglutinin; and virus uptake and endocytosis for antigen presentaBacterial modulins: a novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesisEndotoxin{middle dot}albumin complexes transfer endotoxin monomers to MD-2 resulting in activation of TLR4Antibodies against CD14 protect primates from endotoxin-induced shockReplacement of the glycoinositol phospholipid anchor of Drosophila acetylcholinesterase with a transmembrane domain does not alter sorting in neurons and epithelia but results in behavioral defects.Integrin-directed modulation of macrophage responses to biomaterials.Soluble CD14 truncated at amino acid 152 binds lipopolysaccharide (LPS) and enables cellular response to LPS.A region of human CD14 required for lipopolysaccharide binding.A novel Escherichia coli lipid A mutant that produces an antiinflammatory lipopolysaccharide.Diphosphoryl lipid A from Rhodobacter sphaeroides transiently activates NF-kappa B but inhibits lipopolysaccharide induction of kappa light chain and Oct-2 in the B-cell lymphoma line 70Z/3.Binding of lipopolysaccharide (LPS) to an 80-kilodalton membrane protein of human cells is mediated by soluble CD14 and LPS-binding protein.Glycosphingolipids from Sphingomonas paucimobilis induce monokine production in human mononuclear cells.The N-terminal half of membrane CD14 is a functional cellular lipopolysaccharide receptorHelicobacter pylori lipopolysaccharide can activate 70Z/3 cells via CD14Characterization of a mutant cell line that does not activate NF-kappaB in response to multiple stimuli.Role of protein tyrosine kinase p53/56lyn in diminished lipopolysaccharide priming of formylmethionylleucyl- phenylalanine-induced superoxide production in human newborn neutrophils.Dual receptors and distinct pathways mediate interleukin-1 receptor-associated kinase degradation in response to lipopolysaccharide. Involvement of CD14/TLR4, CR3, and phosphatidylinositol 3-kinase.Endotoxin-neutralizing effects of histidine-rich peptides.Role of MyD88 in diminished tumor necrosis factor alpha production by newborn mononuclear cells in response to lipopolysaccharide.Regions of the mouse CD14 molecule required for toll-like receptor 2- and 4-mediated activation of NF-kappa B.The origin of the synergistic effect of muramyl dipeptide with endotoxin and peptidoglycan.Important role of membrane-associated CD14 in the induction of IFN-beta and subsequent nitric oxide production by murine macrophages in response to bacterial lipopolysaccharide.
P2860
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P2860
Glycosyl-phosphatidylinositol-anchored or integral membrane forms of CD14 mediate identical cellular responses to endotoxin
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Glycosyl-phosphatidylinositol- ...... ellular responses to endotoxin
@ast
Glycosyl-phosphatidylinositol- ...... ellular responses to endotoxin
@en
type
label
Glycosyl-phosphatidylinositol- ...... ellular responses to endotoxin
@ast
Glycosyl-phosphatidylinositol- ...... ellular responses to endotoxin
@en
prefLabel
Glycosyl-phosphatidylinositol- ...... ellular responses to endotoxin
@ast
Glycosyl-phosphatidylinositol- ...... ellular responses to endotoxin
@en
P2093
P2860
P356
P1476
Glycosyl-phosphatidylinositol- ...... ellular responses to endotoxin
@en
P2093
A Moriarty
P S Tobias
R J Ulevitch
T N Kirkland
V Kravchenko
P2860
P304
P356
10.1073/PNAS.90.21.9930
P407
P577
1993-11-01T00:00:00Z