Defective retinal vascular endothelial cell development as a consequence of impaired integrin αVβ8-mediated activation of transforming growth factor-β.
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Vascularisation of the central nervous systemEndothelial expression of TGFβ type II receptor is required to maintain vascular integrity during postnatal development of the central nervous systemA functional requirement for astroglia in promoting blood vessel development in the early postnatal brainExcessive vascular sprouting underlies cerebral hemorrhage in mice lacking αVβ8-TGFβ signaling in the brain.The role of integrins in TGFβ activation in the tumour stromaRegulation of the nascent brain vascular network by neural progenitorsAstrocytic TGF-β signaling limits inflammation and reduces neuronal damage during central nervous system Toxoplasma infection.αvβ8 integrin interacts with RhoGDI1 to regulate Rac1 and Cdc42 activation and drive glioblastoma cell invasion.Modulation of radiation injury response in retinal endothelial cells by quinic acid derivative KZ-41 involves p38 MAPK.Protein tyrosine phosphatase-PEST and β8 integrin regulate spatiotemporal patterns of RhoGDI1 activation in migrating cellsThe αvβ1 integrin plays a critical in vivo role in tissue fibrosis.SOCS3 in retinal neurons and glial cells suppresses VEGF signaling to prevent pathological neovascular growthNeuropilin 1 balances β8 integrin-activated TGFβ signaling to control sprouting angiogenesis in the brainMatrix metalloproteinase-13 mediated degradation of hyaluronic acid-based matrices orchestrates stem cell engraftment through vascular integration.Regulation of TGFβ in the immune system: an emerging role for integrins and dendritic cells.Neurovascular development and links to disease.VEGF, Notch and TGFβ/BMPs in regulation of sprouting angiogenesis and vascular patterning.Neural Regulation of CNS Angiogenesis During Development.αv-Integrin isoform expression in primary human tumors and brain metastases.Glioblastoma stem cells exploit the αvβ8 integrin-TGFβ1 signaling axis to drive tumor initiation and progression.The expanding role of neuropilin: regulation of transforming growth factor-β and platelet-derived growth factor signaling in the vasculatureThe Cytoskeletal Adapter Protein Spinophilin Regulates Invadopodia Dynamics and Tumor Cell Invasion in Glioblastoma.Cutting Edge: Active TGF-β1 Released from GARP/TGF-β1 Complexes on the Surface of Stimulated Human B Lymphocytes Increases Class-Switch Recombination and Production of IgA.A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis.Neural deletion of Tgfbr2 impairs angiogenesis through an altered secretome.Blocking immunosuppression by human Tregs in vivo with antibodies targeting integrin αVβ8.Role of GARP in the activation of latent TGF-β1.Laminin-Dependent Interaction between Astrocytes and Microglia: A Role in Retinal Angiogenesis.Capillary pericytes express α-smooth muscle actin, which requires prevention of filamentous-actin depolymerization for detection.
P2860
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P2860
Defective retinal vascular endothelial cell development as a consequence of impaired integrin αVβ8-mediated activation of transforming growth factor-β.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Defective retinal vascular end ...... transforming growth factor-β.
@ast
Defective retinal vascular end ...... transforming growth factor-β.
@en
type
label
Defective retinal vascular end ...... transforming growth factor-β.
@ast
Defective retinal vascular end ...... transforming growth factor-β.
@en
prefLabel
Defective retinal vascular end ...... transforming growth factor-β.
@ast
Defective retinal vascular end ...... transforming growth factor-β.
@en
P2093
P2860
P1476
Defective retinal vascular end ...... transforming growth factor-β.
@en
P2093
Eric J Huang
Gina M Ferrero
Haiyan Qiu
Isabella T Phan
Louis F Reichardt
Rosemary J Akhurst
Thomas D Arnold
P2860
P304
P356
10.1523/JNEUROSCI.5648-11.2012
P407
P577
2012-01-01T00:00:00Z