Tgfbeta signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development
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Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected]Epicardial Epithelial-to-Mesenchymal Transition in Heart Development and DiseaseMicroRNAs in congenital heart diseaseEndocardial and epicardial epithelial to mesenchymal transitions in heart development and diseaseMatrix control of transforming growth factor-β functionEndothelial expression of TGFβ type II receptor is required to maintain vascular integrity during postnatal development of the central nervous systemSignaling via the Tgf-beta type I receptor Alk5 in heart developmentSpectrum of heart disease associated with murine and human GATA4 mutationLigand-specific function of transforming growth factor beta in epithelial-mesenchymal transition in heart developmentEndoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation.Critical roles of miRNA-mediated regulation of TGFβ signalling during mouse cardiogenesis.Recapitulation of developing artery muscularization in pulmonary hypertension.Myocardial smad4 is essential for cardiogenesis in mouse embryos.Deletion of exon 20 of the Familial Dysautonomia gene Ikbkap in mice causes developmental delay, cardiovascular defects, and early embryonic lethalityMyocardial deletion of Smad4 using a novel α skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tractRare copy number variations in congenital heart disease patients identify unique genes in left-right patterning.Curtailing endothelial TGF-β signaling is sufficient to reduce endothelial-mesenchymal transition and fibrosis in CKDGeneration of a tamoxifen inducible Tnnt2MerCreMer knock-in mouse model for cardiac studiesTransforming growth factor beta signaling in adult cardiovascular diseases and repair.Atrioventricular valve development: new perspectives on an old theme.Partitioning the heart: mechanisms of cardiac septation and valve developmentPdgfrb is a direct regulatory target of TGFβ signaling in atrioventricular cushion mesenchymal cells.Defective retinal vascular endothelial cell development as a consequence of impaired integrin αVβ8-mediated activation of transforming growth factor-β.Spatial regulation of cell cohesion by Wnt5a during second heart field progenitor deployment.Multiple transforming growth factor-beta isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart.Functional BMP receptor in endocardial cells is required in atrioventricular cushion mesenchymal cell formation in chickTGF-β signaling in endothelial cells, but not neuroepithelial cells, is essential for cerebral vascular developmentTbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis.TGFβ signaling and congenital heart disease: Insights from mouse studies.What chick and mouse models have taught us about the role of the endocardium in congenital heart disease.Collagen gel analysis of epithelial-mesenchymal transition in the embryo heart: an in vitro model system for the analysis of tissue interaction, signal transduction, and environmental effects.Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development.The mysterious pathways of cardiac myxomas: a review of histogenesis, pathogenesis and pathology.Dysregulated endocardial TGFβ signaling and mesenchymal transformation result in heart outflow tract septation failure.Roles of TGF-β signals in endothelial-mesenchymal transition during cardiac fibrosisPolycomb repressive complex 2 regulates normal development of the mouse heartLong form of latent TGF-β binding protein 1 (Ltbp1L) regulates cardiac valve development.Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension.A novel BMPR2 gene mutation associated with exercise-induced pulmonary hypertension in septal defects.Hand2 is an essential regulator for two Notch-dependent functions within the embryonic endocardium.
P2860
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P2860
Tgfbeta signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development
description
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Oktober 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/11/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/11/01)
@nl
наукова стаття, опублікована в листопаді 2006
@uk
مقالة علمية (نشرت في نوفمبر 2006)
@ar
name
Tgfbeta signaling is required ...... ng in vivo cardiac development
@ast
Tgfbeta signaling is required ...... ng in vivo cardiac development
@en
Tgfbeta signaling is required ...... ng in vivo cardiac development
@nl
type
label
Tgfbeta signaling is required ...... ng in vivo cardiac development
@ast
Tgfbeta signaling is required ...... ng in vivo cardiac development
@en
Tgfbeta signaling is required ...... ng in vivo cardiac development
@nl
prefLabel
Tgfbeta signaling is required ...... ng in vivo cardiac development
@ast
Tgfbeta signaling is required ...... ng in vivo cardiac development
@en
Tgfbeta signaling is required ...... ng in vivo cardiac development
@nl
P2093
P921
P356
P1433
P1476
Tgfbeta signaling is required ...... ng in vivo cardiac development
@en
P2093
Chris B Brown
H Scott Baldwin
Lorene Batts
Melissa Langworthy
P304
P356
10.1242/DEV.02597
P407
P577
2006-10-18T00:00:00Z