Synthesis and biological evaluation of a new series of 1,2,4-triazolo[1,5-a]-1,3,5-triazines as human A(2A) adenosine receptor antagonists with improved water solubility.
about
Privileged s-triazines: structure and pharmacological applications.History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents.Multivalent approaches and beyond: novel tools for the investigation of dopamine D2 receptor pharmacology.The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A1 and A2A receptor affinity and selectivity profiles.Impact of protein-ligand solvation and desolvation on transition state thermodynamic properties of adenosine A2A ligand binding kinetics.Binding mode similarity measures for ranking of docking poses: a case study on the adenosine A2A receptor.
P2860
Synthesis and biological evaluation of a new series of 1,2,4-triazolo[1,5-a]-1,3,5-triazines as human A(2A) adenosine receptor antagonists with improved water solubility.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Synthesis and biological evalu ...... ith improved water solubility.
@ast
Synthesis and biological evalu ...... ith improved water solubility.
@en
type
label
Synthesis and biological evalu ...... ith improved water solubility.
@ast
Synthesis and biological evalu ...... ith improved water solubility.
@en
prefLabel
Synthesis and biological evalu ...... ith improved water solubility.
@ast
Synthesis and biological evalu ...... ith improved water solubility.
@en
P2093
P2860
P50
P356
P1476
Synthesis and biological evalu ...... ith improved water solubility.
@en
P2093
Barbara Cacciari
Giampiero Spalluto
Giorgia Pastorin
Jeffrey Siegel
Karl Norbert Klotz
Stefano Stragliotto
P2860
P304
P356
10.1021/JM101349U
P407
P577
2011-01-07T00:00:00Z