about
Synthesis and biological evaluation of a new series of 1,2,4-triazolo[1,5-a]-1,3,5-triazines as human A(2A) adenosine receptor antagonists with improved water solubility.The A3 adenosine receptor as multifaceted therapeutic target: pharmacology, medicinal chemistry, and in silico approaches.The significance of 2-furyl ring substitution with a 2-(para-substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA(3) adenosine receptors antagonists: new insights into structure-affinity relationOrganoruthenium antagonists of human A₃ adenosine receptors.Discovery of simplified N²-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: efficient synthetic approaches, biological evaluations and molecular docking studies.Does the combination of optimal substitutions at the C²-, N⁵- and N⁸-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A₃ adenosine receptors?Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists.A facile and novel synthesis of N2-, C6-substituted pyrazolo[3,4-d]pyrimidine-4 carboxylate derivatives as adenosine receptor antagonists
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Siew Lee Cheong
@ast
Siew Lee Cheong
@en
Siew Lee Cheong
@es
Siew Lee Cheong
@nl
Siew Lee Cheong
@sl
type
label
Siew Lee Cheong
@ast
Siew Lee Cheong
@en
Siew Lee Cheong
@es
Siew Lee Cheong
@nl
Siew Lee Cheong
@sl
prefLabel
Siew Lee Cheong
@ast
Siew Lee Cheong
@en
Siew Lee Cheong
@es
Siew Lee Cheong
@nl
Siew Lee Cheong
@sl
P106
P1153
56152330800
P31
P496
0000-0001-6922-6540