about
The PICALM protein plays a key role in iron homeostasis and cell proliferationThe conserved PHD1-PHD2 domain of ZFP-1/AF10 is a discrete functional module essential for viability in Caenorhabditis elegansIdentification of novel pathogenic copy number aberrations in multiple myeloma: the Malaysian contextThe clathrin assembly protein PICALM is required for erythroid maturation and transferrin internalization in mice.Clathrin assembly protein CALM plays a critical role in KIT signaling by regulating its cellular transport from early to late endosomes in hematopoietic cells.NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insightsCCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements.Gene expression profiling and candidate gene resequencing identifies pathways and mutations important for malignant transformation caused by leukemogenic fusion genes.A CALM-derived nuclear export signal is essential for CALM-AF10-mediated leukemogenesis.GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancerIsolated Hoxa9 overexpression predisposes to the development of lymphoid but not myeloid leukemia.A chromatin modifier integrates insulin/IGF-1 signalling and dietary restriction to regulate longevity.Targeting DOT1L action and interactions in leukemia: the role of DOT1L in transformation and development.Lymphadenopathy and hepatosplenomegaly in a patient with acute myelogenous leukaemia.The CALM and CALM/AF10 interactor CATS is a marker for proliferation.Non-homologous end joining mediated DNA repair is impaired in the NUP98-HOXD13 mouse model for myelodysplastic syndrome.Induced myelomonocytic differentiation in leukemia cells is accompanied by noncanonical transcription factor expression.Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance.Detection of PICALM-MLLT10 (CALM-AF10) and outcome in children with T-lineage acute lymphoblastic leukemia.Phenotypic and genetic characterization of adult T-cell acute lymphoblastic leukemia with del(9)(q34);SET-NUP214 rearrangement.CALM/AF10-positive leukemias show upregulation of genes involved in chromatin assembly and DNA repair processes and of genes adjacent to the breakpoint at 10p12.Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor geneAcute myeloid leukemiaAcute Myeloid Leukemia
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The role of CALM-AF10 gene fusion in acute leukemia.
@ast
The role of CALM-AF10 gene fusion in acute leukemia.
@en
type
label
The role of CALM-AF10 gene fusion in acute leukemia.
@ast
The role of CALM-AF10 gene fusion in acute leukemia.
@en
prefLabel
The role of CALM-AF10 gene fusion in acute leukemia.
@ast
The role of CALM-AF10 gene fusion in acute leukemia.
@en
P2860
P356
P1433
P1476
The role of CALM-AF10 gene fusion in acute leukemia.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.LEU.2405074
P577
2007-12-20T00:00:00Z
P5875
P6179
1005747653