A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia
about
MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25)The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein familyThe leucine zipper motif of the Drosophila AF10 homologue can inhibit PRE-mediated repression: implications for leukemogenic activity of human MLL-AF10 fusionst(11;22)(q23;q11.2) In acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromesIdentification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 geneA network of HSPG core proteins and HS modifying enzymes regulates netrin-dependent guidance of D-type motor neurons in Caenorhabditis elegansThe leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasisNeuronal migration is regulated by endogenous RNAi and chromatin-binding factor ZFP-1/AF10 in Caenorhabditis elegansThe conserved PHD1-PHD2 domain of ZFP-1/AF10 is a discrete functional module essential for viability in Caenorhabditis elegansConstruction of a high-resolution 2.5-Mb transcript map of the human 6p21.2-6p21.3 region immediately centromeric of the major histocompatibility complex.Domains with transcriptional regulatory activity within the ALL1 and AF4 proteins involved in acute leukemia.The leukemia-associated-protein (LAP) domain, a cysteine-rich motif, is present in a wide range of proteins, including MLL, AF10, and MLLT6 proteins.Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.A conserved PHD finger protein and endogenous RNAi modulate insulin signaling in Caenorhabditis elegansUsing RNA interference to identify genes required for RNA interference.AF10 plays a key role in the survival of uncommitted hematopoietic cells.Widely expressed Af17 is likely not required for embryogenesis, hematopoiesis, and animal survival.Panhandle PCR for cDNA: a rapid method for isolation of MLL fusion transcripts involving unknown partner genes.FHL2 interacts with CALM and is highly expressed in acute erythroid leukemia.'Chromosomal Rainbows' Detect Oncogenic Rearrangements of Signaling Molecules in Thyroid Tumors.Developmental analysis and subcellular localization of the murine homologue of ELL.Gene identification and DNA sequence analysis in the GC-poor 20 megabase region of human chromosome 21Genetic aberrations in glioblastoma multiforme: translocation of chromosome 10 in an O-2A-like cell line.The role of CALM-AF10 gene fusion in acute leukemia.AF17 competes with AF9 for binding to Dot1a to up-regulate transcription of epithelial Na+ channel alpha.Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l.Functional analysis of the leukemia protein ELL: evidence for a role in the regulation of cell growth and survival.Loss of LIN-35, the Caenorhabditis elegans ortholog of the tumor suppressor p105Rb, results in enhanced RNA interference.Molecular studies reveal MLL-MLLT10/AF10 and ARID5B-MLL gene fusions displaced in a case of infantile acute lymphoblastic leukemia with complex karyotype.Identification of GSX2 and AF10 as NUP98 partner genes in myeloid malignancies.Identification of pleiotropic cancer susceptibility variants from genome-wide association studies reveals functional characteristics.
P2860
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P2860
A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia
description
1995 nî lūn-bûn
@nan
1995 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մարտին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A novel class of zinc finger/l ...... ranslocation in acute leukemia
@ast
A novel class of zinc finger/l ...... ranslocation in acute leukemia
@en
A novel class of zinc finger/l ...... ranslocation in acute leukemia
@en-gb
A novel class of zinc finger/l ...... ranslocation in acute leukemia
@nl
type
label
A novel class of zinc finger/l ...... ranslocation in acute leukemia
@ast
A novel class of zinc finger/l ...... ranslocation in acute leukemia
@en
A novel class of zinc finger/l ...... ranslocation in acute leukemia
@en-gb
A novel class of zinc finger/l ...... ranslocation in acute leukemia
@nl
prefLabel
A novel class of zinc finger/l ...... ranslocation in acute leukemia
@ast
A novel class of zinc finger/l ...... ranslocation in acute leukemia
@en
A novel class of zinc finger/l ...... ranslocation in acute leukemia
@en-gb
A novel class of zinc finger/l ...... ranslocation in acute leukemia
@nl
P2093
P921
P1433
P1476
A novel class of zinc finger/l ...... ranslocation in acute leukemia
@en
P2093
Della Valle V
Gregorini A
Lillington D
P304
P407
P577
1995-03-01T00:00:00Z