Spontaneous substitutions in the vicinity of the V3 analog affect cell tropism and pathogenicity of simian immunodeficiency virus.
about
Induction of AIDS by simian immunodeficiency virus from an African green monkey: species-specific variation in pathogenicity correlates with the extent of in vivo replication.Viral genetic evolution in macaques infected with molecularly cloned simian immunodeficiency virus correlates with the extent of persistent viremia.Rhesus macaques infected with macrophage-tropic simian immunodeficiency virus (SIVmacR71/17E) exhibit extensive focal segmental and global glomerulosclerosis.Characterization of a macaque recombinant monoclonal antibody that binds to a CD4-induced epitope and neutralizes simian immunodeficiency virusAbility of the V3 loop of simian immunodeficiency virus to serve as a target for antibody-mediated neutralization: correlation of neutralization sensitivity, growth in macrophages, and decreased dependence on CD4Fusogenic selectivity of the envelope glycoprotein is a major determinant of human immunodeficiency virus type 1 tropism for CD4+ T-cell lines vs. primary macrophagesInfectious molecular clones from a simian immunodeficiency virus-infected rapid-progressor (RP) macaque: evidence of differential selection of RP-specific envelope mutations in vitro and in vivoUnique pattern of convergent envelope evolution in simian immunodeficiency virus-infected rapid progressor macaques: association with CD4-independent usage of CCR5.Regions required for CD4 binding in the external glycoprotein gp120 of simian immunodeficiency virusV3-independent determinants of macrophage tropism in a primary human immunodeficiency virus type 1 isolate.An infectious chimeric human immunodeficiency virus type 2 (HIV-2) expressing the HIV-1 principal neutralizing determinant.An env gene derived from a primary human immunodeficiency virus type 1 isolate confers high in vivo replicative capacity to a chimeric simian/human immunodeficiency virus in rhesus monkeysCell type-specific fusion cofactors determine human immunodeficiency virus type 1 tropism for T-cell lines versus primary macrophages.A molecularly cloned, pathogenic, neutralization-resistant simian immunodeficiency virus, SIVsmE543-3.Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entryShared usage of the chemokine receptor CXCR4 by the feline and human immunodeficiency viruses.A rapid progressor-specific variant clone of simian immunodeficiency virus replicates efficiently in vivo only in the absence of immune responses.Extensive envelope heterogeneity of simian immunodeficiency virus in tissues from infected macaques.A simian immunodeficiency virus envelope V3 cytotoxic T-lymphocyte epitope in rhesus monkeys and its restricting major histocompatibility complex class I molecule Mamu-A*02.CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strainStructured-tree topology and adaptive evolution of the simian immunodeficiency virus SIVsm envelope during serial passage in rhesus macaques according to likelihood mapping and quartet puzzling.Simian immunodeficiency virus variants with differential T-cell and macrophage tropism use CCR5 and an unidentified cofactor expressed in CEMx174 cells for efficient entry.Biological, molecular, and structural analysis of a cytopathic variant from a molecularly cloned simian immunodeficiency virus.
P2860
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P2860
Spontaneous substitutions in the vicinity of the V3 analog affect cell tropism and pathogenicity of simian immunodeficiency virus.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Spontaneous substitutions in t ...... simian immunodeficiency virus.
@ast
Spontaneous substitutions in t ...... simian immunodeficiency virus.
@en
type
label
Spontaneous substitutions in t ...... simian immunodeficiency virus.
@ast
Spontaneous substitutions in t ...... simian immunodeficiency virus.
@en
prefLabel
Spontaneous substitutions in t ...... simian immunodeficiency virus.
@ast
Spontaneous substitutions in t ...... simian immunodeficiency virus.
@en
P2093
P2860
P1433
P1476
Spontaneous substitutions in t ...... simian immunodeficiency virus.
@en
P2093
Dapolito G
Goldstein S
Johnson PR
P2860
P304
P407
P577
1994-04-01T00:00:00Z