Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer - Wikidata - awgldk - TriplyDB

Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer

Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer

http://www.wikidata.org/entity/Q36637020

about

S100A1: a regulator of myocardial contractility Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction Enhanced beta2-adrenergic receptor (beta2AR) signaling by adeno-associated viral (AAV)-mediated gene transfer GRK2 in the heart: a GPCR kinase and beyond New advances in beta-blocker therapy in heart failure Cardiovascular gene therapy for myocardial infarction The inotropic peptide βARKct improves βAR responsiveness in normal and failing cardiomyocytes through G(βγ)-mediated L-type calcium current disinhibition.Dual modulation of cell survival and cell death by beta(2)-adrenergic signaling in adult mouse cardiac myocytes G-protein coupled receptor kinases as modulators of G-protein signalling.Prospects for xenotransplantation.Regulation of cardiac contractility by Rab4-modulated beta2-adrenergic receptor recycling.Recombinant, replication-defective adenovirus gene transfer vectors induce cell cycle dysregulation and inappropriate expression of cyclin proteins.Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary beta2-adrenergic receptor gene delivery Reversal of impaired myocardial beta-adrenergic receptor signaling by continuous-flow left ventricular assist device support.G-protein βγ subunit dimers modulate kidney repair after ischemia-reperfusion injury in rats.Genetic manipulation of beta-adrenergic signalling in heart failure.The future promises of xenotransplantation.Therapeutic strategies for xenograft rejection.Genetic therapies and xenotransplantation.Targeting calcium cycling proteins in heart failure through gene transfer.Emerging therapeutic targets in chronic heart failure: part II.Targeting signaling pathways in heart failure by gene transfer.Crosstalk between Gi and Gq/Gs pathways in airway smooth muscle regulates bronchial contractility and relaxation.Alveolar epithelial beta 2-adrenergic receptors: their role in regulation of alveolar active sodium transport.Augmenting beta receptors in the heart: short-term gains offset by long-term pains?Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice.Targeting Gbeta gamma signaling in arterial vascular smooth muscle proliferation: a novel strategy to limit restenosis.Central role of Gq in the hypertrophic signal transduction of angiotensin II in vascular smooth muscle cells.Engineering blood vessels by gene and cell therapy.Alveolar epithelial beta2-adrenergic receptors.Gene therapy in heart failure.Uncoupling of myocardial beta-adrenergic receptor signaling during coronary artery bypass grafting: the role of GRK2.Designing heart performance by gene transfer.The Ile164 beta2-adrenergic receptor polymorphism adversely affects the outcome of congestive heart failure.GRK2 as a novel gene therapy target in heart failure.G protein-coupled receptor kinases in normal and failing myocardium.Molecular targeting of Gα and Gβγ subunits: a potential approach for cancer therapeutics.Gene therapy for heart disease: molecular targets, vectors and modes of delivery to myocardium.G protein-independent inhibition of GIRK current by adenosine in rat atrial myocytes overexpressing A1 receptors after adenovirus-mediated gene transfer.Promise of adeno-associated virus as a gene therapy vector for cardiovascular diseases.

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Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer

http://www.wikidata.org/entity/Q36637020

description

1997 nî lūn-bûn

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1997年論文

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1997年論文

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1997年论文

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name

Restoration of beta-adrenergic ...... noviral-mediated gene transfer

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Restoration of beta-adrenergic ...... noviral-mediated gene transfer

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Restoration of beta-adrenergic ...... noviral-mediated gene transfer

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Restoration of beta-adrenergic ...... noviral-mediated gene transfer

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PNAS.94.22.12100

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Proceedings of the National Academy of Sciences of the United States of America

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Restoration of beta-adrenergic ...... noviral-mediated gene transfer

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A P Kypson

http://www.w3.org/2001/XMLSchema#string

C A Skaer

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D D Glower

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K C Peppel

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P H McDonald

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R J Lefkowitz

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S A Akhter

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W J Koch

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P2860

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor

Increase of the 40,000-mol wt pertussis toxin substrate (G protein) in the failing human heart

Reduced beta-adrenergic receptor activation decreases G-protein expression and beta-adrenergic receptor kinase activity in porcine heart

Potentiation of beta-adrenergic signaling by adenoviral-mediated gene transfer in adult rabbit ventricular myocytes

G-protein-coupled receptor kinase activity is increased in hypertension.

Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice.

Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases.

Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart.

Low-dose inotropic therapy for ambulatory heart failure.

Structure and mechanism of the G protein-coupled receptor kinases.

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12100-12105

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10.1073/PNAS.94.22.12100

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94

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13886715

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9342369

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23716

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