The sirtuin family's role in aging and age-associated pathologies. - Wikidata - awgldk - TriplyDB

The sirtuin family's role in aging and age-associated pathologies.

The sirtuin family's role in aging and age-associated pathologies.

http://www.wikidata.org/entity/Q36638121

about

Emerging therapeutic roles for NAD(+) metabolism in mitochondrial and age-related disorders Oxidative stress and mitochondrial damage: importance in non-SOD1 ALS Modelling age-related metabolic disorders in the mouse Nonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylases Sending Out an SOS: Mitochondria as a Signaling Hub Adaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous system Small-molecule allosteric activators of sirtuins.Functional genetic variants within the SIRT2 gene promoter in acute myocardial infarction.Cardioprotective Effects of SIRT6 in a Mouse Model of Transverse Aortic Constriction-Induced Heart Failure.Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism.Sirtuins: guardians of mammalian healthspan.Emerging role of sirtuins on tumorigenesis: possible link between aging and cancer The "metabolic winter" hypothesis: a cause of the current epidemics of obesity and cardiometabolic disease.Interferon regulatory factor 9 is critical for neointima formation following vascular injury Sirtuins, aging, and cardiovascular risks.NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus The Histone Deacetylase Sirtuin 1 Is Reduced in Systemic Sclerosis and Abrogates Fibrotic Responses by Targeting Transforming Growth Factor β Signaling.Metabolic Regulation by Lysine Malonylation, Succinylation, and Glutarylation.Caffeic acid ethanolamide prevents cardiac dysfunction through sirtuin dependent cardiac bioenergetics preservation.A Label-free Sirtuin 1 Assay based on Droplet-Electrospray Ionization Mass Spectrometry Sirtuin-dependent clock control: new advances in metabolism, aging and cancer Genome-wide transcriptomics of aging in the rotifer Brachionus manjavacas, an emerging model system.AMPK, insulin resistance, and the metabolic syndrome.Prolactin protects retinal pigment epithelium by inhibiting sirtuin 2-dependent cell death Roles of NAD (+) , PARP-1, and Sirtuins in Cell Death, Ischemic Brain Injury, and Synchrotron Radiation X-Ray-Induced Tissue Injury.Lifespan extension by cranberry supplementation partially requires SOD2 and is life stage independent.The Role of Clinical Proteomics, Lipidomics, and Genomics in the Diagnosis of Alzheimer's Disease.Adult Stem Cells and Diseases of Aging.Drugs that modulate aging: the promising yet difficult path ahead.Melatonin and the theories of aging: a critical appraisal of melatonin's role in antiaging mechanisms.Epigenetic pathway targets for the treatment of disease: accelerating progress in the development of pharmacological tools: IUPHAR Review 11.Epigenetics of hematopoietic stem cell aging and disease.Sirtuins and the circadian clock: bridging chromatin and metabolism.Molecular pathways of arterial aging.Angiotensin II blockade: how its molecular targets may signal to mitochondria and slow aging. Coincidences with calorie restriction and mTOR inhibition.Protein acetylation in metabolism - metabolites and cofactors.New concept: cellular senescence in pathophysiology of cholangiocarcinoma.Molecular and biological hallmarks of ageing.Sirtuin 3 inhibits hepatocellular carcinoma growth through the glycogen synthase kinase-3β/BCL2-associated X protein-dependent apoptotic pathway.Sirtuins, a promising target in slowing down the ageing process.

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P2860

The sirtuin family's role in aging and age-associated pathologies.

http://www.wikidata.org/entity/Q36638121

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

The sirtuin family's role in aging and age-associated pathologies.

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The sirtuin family's role in aging and age-associated pathologies.

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The sirtuin family's role in aging and age-associated pathologies.

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The sirtuin family's role in aging and age-associated pathologies.

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The sirtuin family's role in aging and age-associated pathologies.

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The sirtuin family's role in aging and age-associated pathologies.

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Journal of Clinical Investigation

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The sirtuin family's role in aging and age-associated pathologies.

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P2093

Jessica A Hall

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John E Dominy

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Pere Puigserver

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Yoonjin Lee

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P2860

SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity

Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ

Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

SIRT1 deacetylates and positively regulates the nuclear receptor LXR

Human SIRT6 promotes DNA end resection through CtIP deacetylation

Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation

SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis

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973-979

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10.1172/JCI64094

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3

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123

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2013-03-01T00:00:00Z

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