Multiple viral determinants contribute to pathogenicity of the acutely lethal simian immunodeficiency virus SIVsmmPBj variant.
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Going wild: lessons from naturally occurring T-lymphotropic lentivirusesInduction of AIDS by simian immunodeficiency virus from an African green monkey: species-specific variation in pathogenicity correlates with the extent of in vivo replication.Impact of viral factors on very early in vivo replication profiles in simian immunodeficiency virus SIVagm-infected African green monkeys.Isolation and characterization of a neuropathogenic simian immunodeficiency virus derived from a sooty mangabey.Postinoculation PMPA treatment, but not preinoculation immunomodulatory therapy, protects against development of acute disease induced by the unique simian immunodeficiency virus SIVsmmPBj.Biologic studies of chimeras of highly and moderately virulent molecular clones of simian immunodeficiency virus SIVsmPBj suggest a critical role for envelope in acute AIDS virus pathogenesis.Characteristics of a pathogenic molecular clone of an end-stage serum-derived variant of simian immunodeficiency virus (SIV(F359)).Development and characterization of an in vivo pathogenic molecular clone of equine infectious anemia virus.Increased mucosal transmission but not enhanced pathogenicity of the CCR5-tropic, simian AIDS-inducing simian/human immunodeficiency virus SHIV(SF162P3) maps to envelope gp120.The U3 promoter region of the acutely lethal simian immunodeficiency virus clone smmPBj1.9 confers related biological activity on the apathogenic clone agm3mc.Nonpathogenic CCR2-tropic SIVrcm after serial passage and its effect on SIVmac infection of Indian rhesus macaques.The ITAM in Nef influences acute pathogenesis of AIDS-inducing simian immunodeficiency viruses SIVsm and SIVagm without altering kinetics or extent of viremiaAn acutely lethal simian immunodeficiency virus stimulates expansion of V beta 7- and V beta 14-expressing T lymphocytes.Induction of lymphocyte proliferation and severe gastrointestinal disease in macaques by a nef gene variant SIVmac239.Characterization of an infectious molecular clone of human T-cell leukemia virus type I.Molecular and biological analyses of quasispecies during evolution of a virulent simian immunodeficiency virus, SIVsmmPBj14.Genomic quasispecies associated with the initiation of infection and disease in ponies experimentally infected with equine infectious anemia virus.Identification of a replication-competent pathogenic human immunodeficiency virus type 1 with a duplication in the TCF-1alpha region but lacking NF-kappaB binding sitesThe cytopathicity of a simian immunodeficiency virus Mne variant is determined by mutations in Gag and Env.Immune activation and viral burden in acute disease induced by simian immunodeficiency virus SIVsmmPBj14: correlation between in vitro and in vivo events.Viral determinants of simian immunodeficiency virus (SIV) virulence in rhesus macaques assessed by using attenuated and pathogenic molecular clones of SIVmacAnalysis of simian immunodeficiency virus sequence variation in tissues of rhesus macaques with simian AIDSHeterogeneity in neutralization sensitivities of viruses comprising the simian immunodeficiency virus SIVsmE660 isolate and vaccine challenge stock.Evolution of a simian immunodeficiency virus pathogen.Changes in the extracellular envelope glycoprotein of variants that evolve during the course of simian immunodeficiency virus SIVMne infection affect neutralizing antibody recognition, syncytium formation, and macrophage tropism but not replication,Characterization of the Jembrana disease virus tat gene and the cis- and trans-regulatory elements in its long terminal repeats.Limited protection from a pathogenic chimeric simian-human immunodeficiency virus challenge following immunization with attenuated simian immunodeficiency virus.A lymph node-derived cytopathic simian immunodeficiency virus Mne variant replicates in nonstimulated peripheral blood mononuclear cells.Structured-tree topology and adaptive evolution of the simian immunodeficiency virus SIVsm envelope during serial passage in rhesus macaques according to likelihood mapping and quartet puzzling.The U3 promoter and the nef gene of simian immunodeficiency virus (SIV) smmPBj1.9 do not confer acute pathogenicity upon SIVagm.Mortality among human immunodeficiency virus type 2-positive villagers in rural Guinea-Bissau is correlated with viral genotype.Costimulatory pathways in lymphocyte proliferation induced by the simian immunodeficiency virus SIVsmmPBj14.Enhanced responsiveness to nuclear factor kappa B contributes to the unique phenotype of simian immunodeficiency virus variant SIVsmmPBj14.High level of susceptibility to human TRIM5α conferred by HIV-2 capsid sequences.Mutation of a diacidic motif in SIV-PBj Nef impairs T-cell activation and enteropathic disease.
P2860
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P2860
Multiple viral determinants contribute to pathogenicity of the acutely lethal simian immunodeficiency virus SIVsmmPBj variant.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
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1993年论文
@zh-cn
name
Multiple viral determinants co ...... iency virus SIVsmmPBj variant.
@ast
Multiple viral determinants co ...... iency virus SIVsmmPBj variant.
@en
type
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Multiple viral determinants co ...... iency virus SIVsmmPBj variant.
@ast
Multiple viral determinants co ...... iency virus SIVsmmPBj variant.
@en
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Multiple viral determinants co ...... iency virus SIVsmmPBj variant.
@ast
Multiple viral determinants co ...... iency virus SIVsmmPBj variant.
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P2093
P2860
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P1476
Multiple viral determinants co ...... iency virus SIVsmmPBj variant.
@en
P2093
D C Anderson
F J Novembre
H M McClure
P R Johnson
V M Hirsch
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P304
P407
P577
1993-05-01T00:00:00Z