Strand-biased cytosine deamination at the replication fork causes cytosine to thymine mutations in Escherichia coli.
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Toward a microbial Neolithic revolution in buildingsAPOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA ReplicationOptimization of amino acid replacement costs by mutational pressure in bacterial genomesActivation induced deaminase mutational signature overlaps with CpG methylation sites in follicular lymphoma and other cancers.Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair.APOBEC3A damages the cellular genome during DNA replicationFunctional Upregulation of the DNA Cytosine Deaminase APOBEC3B by Polyomaviruses.Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor HeterogeneityCytosine Deaminase APOBEC3A Sensitizes Leukemia Cells to Inhibition of the DNA Replication Checkpoint.Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells.APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast.Functions and Malfunctions of Mammalian DNA-Cytosine DeaminasesAPOBEC3A/B-induced mutagenesis is responsible for 20% of heritable mutations in the TpCpW context.Avoidance of APOBEC3B-induced mutation by error-free lesion bypassRecombination Is Responsible for the Increased Recovery of Drug-Resistant Mutants with Hypermutated Genomes in Resting Yeast Diploids Expressing APOBEC Deaminases.Sources of spontaneous mutagenesis in bacteria.
P2860
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P2860
Strand-biased cytosine deamination at the replication fork causes cytosine to thymine mutations in Escherichia coli.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Strand-biased cytosine deamina ...... mutations in Escherichia coli.
@ast
Strand-biased cytosine deamina ...... mutations in Escherichia coli.
@en
type
label
Strand-biased cytosine deamina ...... mutations in Escherichia coli.
@ast
Strand-biased cytosine deamina ...... mutations in Escherichia coli.
@en
prefLabel
Strand-biased cytosine deamina ...... mutations in Escherichia coli.
@ast
Strand-biased cytosine deamina ...... mutations in Escherichia coli.
@en
P2093
P2860
P356
P1476
Strand-biased cytosine deamina ...... mutations in Escherichia coli
@en
P2093
Ashok S Bhagwat
Haixu Tang
Heewook Lee
Jesse P Townes
Patricia L Foster
P2860
P304
P356
10.1073/PNAS.1522325113
P407
P50
P577
2016-02-02T00:00:00Z