Alternative splicing of human immunodeficiency virus type 1 mRNA modulates viral protein expression, replication, and infectivity.
about
Engineering HIV-1-resistant T-cells from short-hairpin RNA-expressing hematopoietic stem/progenitor cells in humanized BLT miceDual effect of the SR proteins ASF/SF2, SC35 and 9G8 on HIV-1 RNA splicing and virion production.Human immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activityArchitecture and secondary structure of an entire HIV-1 RNA genomeA bidirectional SF2/ASF- and SRp40-dependent splicing enhancer regulates human immunodeficiency virus type 1 rev, env, vpu, and nef gene expressionIdentification of Staufen in the human immunodeficiency virus type 1 Gag ribonucleoprotein complex and a role in generating infectious viral particlesSmall interfering RNAs against the TAR RNA binding protein, TRBP, a Dicer cofactor, inhibit human immunodeficiency virus type 1 long terminal repeat expression and viral productionSplicing of human immunodeficiency virus RNA is position-dependent suggesting sequential removal of introns from the 5' endA suboptimal 5' splice site downstream of HIV-1 splice site A1 is required for unspliced viral mRNA accumulation and efficient virus replicationTranslational Control of the HIV Unspliced Genomic RNASingle-Cell and Single-Cycle Analysis of HIV-1 ReplicationThe Life-Cycle of the HIV-1 Gag-RNA ComplexInteractions between the HIV-1 Unspliced mRNA and Host mRNA Decay MachineriesInsights into the nuclear export of murine leukemia virus intron-containing RNARNA structure modulates splicing efficiency at the human immunodeficiency virus type 1 major splice donorThe HIV-1 Rev response element (RRE) adopts alternative conformations that promote different rates of virus replication.Long lasting control of viral rebound with a new drug ABX464 targeting Rev - mediated viral RNA biogenesis.Functional bottlenecks for generation of HIV-1 intersubtype Env recombinants.A Naturally Occurring rev1-vpu Fusion Gene Does Not Confer a Fitness Advantage to HIV-1.A long-awaited structure is rev-ealed.Identification of new splice sites used for generation of rev transcripts in human immunodeficiency virus type 1 subtype C primary isolates.Trafficking through the Rev/RRE pathway is essential for efficient inhibition of human immunodeficiency virus type 1 by an antisense RNA derived from the envelope gene.The secondary structure of the human immunodeficiency virus type 1 transcript modulates viral splicing and infectivity.Presence of negative and positive cis-acting RNA splicing elements within and flanking the first tat coding exon of human immunodeficiency virus type 1HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA.Acetylated Tat regulates human immunodeficiency virus type 1 splicing through its interaction with the splicing regulator p32.Integration site selection by retroviral vectors: molecular mechanism and clinical consequences.Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAsThermodynamic profiling of HIV RREIIB RNA-zinc finger interactions.A novel HIV-1-encoded microRNA enhances its viral replication by targeting the TATA box region.Multi-Faceted Post-Transcriptional Functions of HIV-1 Rev.Argonaute proteins regulate HIV-1 multiply spliced RNA and viral production in a Dicer independent mannerExpression of Herpes Simplex Virus Thymidine Kinase/Ganciclovir by RNA Trans-Splicing Induces Selective Killing of HIV-Producing Cells.Diminished production of human immunodeficiency virus type 1 in astrocytes results from inefficient translation of gag, env, and nef mRNAs despite efficient expression of Tat and RevRegulation of virus release by the macrophage-tropic human immunodeficiency virus type 1 AD8 isolate is redundant and can be controlled by either Vpu or Env.Serine- and arginine-rich proteins 55 and 75 (SRp55 and SRp75) induce production of HIV-1 vpr mRNA by inhibiting the 5'-splice site of exon 3U1 small nuclear ribonucleoprotein and splicing inhibition by the rous sarcoma virus negative regulator of splicing element.A rev1-vpu polymorphism unique to HIV-1 subtype A and C strains impairs envelope glycoprotein expression from rev-vpu-env cassettes and reduces virion infectivity in pseudotyping assays.The transcriptional transactivator Tat selectively regulates viral splicing.The exon splicing silencer in human immunodeficiency virus type 1 Tat exon 3 is bipartite and acts early in spliceosome assembly.
P2860
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P2860
Alternative splicing of human immunodeficiency virus type 1 mRNA modulates viral protein expression, replication, and infectivity.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Alternative splicing of human ...... replication, and infectivity.
@ast
Alternative splicing of human ...... replication, and infectivity.
@en
type
label
Alternative splicing of human ...... replication, and infectivity.
@ast
Alternative splicing of human ...... replication, and infectivity.
@en
prefLabel
Alternative splicing of human ...... replication, and infectivity.
@ast
Alternative splicing of human ...... replication, and infectivity.
@en
P2860
P1433
P1476
Alternative splicing of human ...... , replication, and infectivity
@en
P2093
P2860
P304
P407
P577
1993-11-01T00:00:00Z