ATF4-dependent transcription mediates signaling of amino acid limitation. - Wikidata - awgldk - TriplyDB

ATF4-dependent transcription mediates signaling of amino acid limitation.

ATF4-dependent transcription mediates signaling of amino acid limitation.

http://www.wikidata.org/entity/Q36655003

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TBL2 is a novel PERK-binding protein that modulates stress-signaling and cell survival during endoplasmic reticulum stress Melanoma and the Unfolded Protein Response Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TOR Differential adaptive responses to 1- or 2-day fasting in various mouse tissues revealed by quantitative PCR analysis Use of a small molecule cell cycle inhibitor to control cell growth and improve specific productivity and product quality of recombinant proteins in CHO cell cultures The brain's response to an essential amino acid-deficient diet and the circuitous route to a better meal Mitochondrial dysfunction remodels one-carbon metabolism in human cells KDM4C and ATF4 Cooperate in Transcriptional Control of Amino Acid Metabolism Cystathionine gamma-Lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury.The eIF2 kinase GCN2 is essential for the murine immune system to adapt to amino acid deprivation by asparaginase dATF4 regulation of mitochondrial folate-mediated one-carbon metabolism is neuroprotective.Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration Amino acids regulate transgene expression in MDCK cells.HIV Exploits Antiviral Host Innate GCN2-ATF4 Signaling for Establishing Viral Replication Early in Infection Role of activating transcription factor 4 in the hepatic response to amino acid depletion by asparaginase.Phosphoinositide 3-kinases upregulate system xc(-) via eukaryotic initiation factor 2α and activating transcription factor 4 - A pathway active in glioblastomas and epilepsy Amino acid homeostasis and signalling in mammalian cells and organisms.Amino acid availability controls TRB3 transcription in liver through the GCN2/eIF2α/ATF4 pathway Expression profiling after activation of amino acid deprivation response in HepG2 human hepatoma cells Acceleration of biliary cholesterol secretion restores glycemic control and alleviates hypertriglyceridemia in obese db/db mice.Glutamine synthetase is a genetic determinant of cell type-specific glutamine independence in breast epithelia.Skeletal muscle Ras-related GTP binding B mRNA and protein expression is increased after essential amino acid ingestion in healthy humans A mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-dependent transcriptional program controls activation of the early growth response 1 (EGR1) gene during amino acid limitation Low amino acids affect expression of 11β-HSD2 in BeWo cells through leptin-activated JAK-STAT and MAPK pathways.The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.Dysregulation of system xc(-) expression induced by mutant huntingtin in a striatal neuronal cell line and in R6/2 mice Indoleamine 2,3 dioxygenase and metabolic control of immune responses.Asparagine synthetase: regulation by cell stress and involvement in tumor biology Cysteine supplementation reverses methionine restriction effects on rat adiposity: significance of stearoyl-coenzyme A desaturase.Signaling dynamics of palmitate-induced ER stress responses mediated by ATF4 in HepG2 cells Cellular IRES-mediated translation: the war of ITAFs in pathophysiological states.Study of global transcriptional changes of N-GlcNAc2 proteins-producing T24 bladder carcinoma cells under glucose deprivation Short-term cuprizone feeding induces selective amino acid deprivation with concomitant activation of an integrated stress response in oligodendrocytes.MAPK signaling triggers transcriptional induction of cFOS during amino acid limitation of HepG2 cells.Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise.Impaired nutrient signaling and body weight control in a Na+ neutral amino acid cotransporter (Slc6a19)-deficient mouse.Elevated ATF4 function in fibroblasts and liver of slow-aging mutant mice.SLC6A14 (ATB0,+) protein, a highly concentrative and broad specific amino acid transporter, is a novel and effective drug target for treatment of estrogen receptor-positive breast cancer.Amino acid catabolism: a pivotal regulator of innate and adaptive immunity.

P2860

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P2860

ATF4-dependent transcription mediates signaling of amino acid limitation.

http://www.wikidata.org/entity/Q36655003

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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2009年论文

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2009年论文

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ATF4-dependent transcription mediates signaling of amino acid limitation.

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ATF4-dependent transcription mediates signaling of amino acid limitation.

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ATF4-dependent transcription mediates signaling of amino acid limitation.

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ATF4-dependent transcription mediates signaling of amino acid limitation.

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ATF4-dependent transcription mediates signaling of amino acid limitation.

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ATF4-dependent transcription mediates signaling of amino acid limitation.

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J.TEM.2009.05.008

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Trends in Endocrinology and Metabolism

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ATF4-dependent transcription mediates signaling of amino acid limitation.

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P2093

Jixiu Shan

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Michael S Kilberg

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Nan Su

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P2860

Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2

ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia

C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene

Identification of novel stress-induced genes downstream of chop

Characterization of the amino acid response element within the human sodium-coupled neutral amino acid transporter 2 (SNAT2) System A transporter gene

The p300/CBP-associated factor (PCAF) is a cofactor of ATF4 for amino acid-regulated transcription of CHOP

Mediator as a general transcription factor.

Transcriptional activation by Gcn4p involves independent interactions with the SWI/SNF complex and the SRB/mediator.

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436-443

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10.1016/J.TEM.2009.05.008

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9

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3587693

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