The UL5 gene of herpes simplex virus type 1: isolation of a lacZ insertion mutant and association of the UL5 gene product with other members of the helicase-primase complex.
about
The DNA helicase-primase complex as a target for herpes viral infectionCurrent and potential treatments for ubiquitous but neglected herpesvirus infectionsA viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responsesThe herpes simplex virus type 1 cleavage/packaging protein, UL32, is involved in efficient localization of capsids to replication compartmentsInhibition of the herpes simplex virus type 1 DNA polymerase induces hyperphosphorylation of replication protein A and its accumulation at S-phase-specific sites of DNA damage during infection.Virus-Induced Chaperone-Enriched (VICE) domains function as nuclear protein quality control centers during HSV-1 infectionConstruction, phenotypic analysis, and immunogenicity of a UL5/UL29 double deletion mutant of herpes simplex virus 2.An intertypic herpes simplex virus helicase-primase complex associated with a defect in neurovirulence has reduced primase activity.HIV integrase inhibitors block replication of alpha-, beta-, and gammaherpesvirusesRole of the herpes simplex virus helicase-primase complex during adeno-associated virus DNA replicationRecruitment of polymerase to herpes simplex virus type 1 replication foci in cells expressing mutant primase (UL52) proteins.Herpes simplex virus type 1 single strand DNA binding protein and helicase/primase complex disable cellular ATR signaling.Conformational changes in the herpes simplex virus ICP8 DNA-binding protein coincident with assembly in viral replication structures.The vaccinia virus D5 protein, which is required for DNA replication, is a nucleic acid-independent nucleoside triphosphatase.Functional order of assembly of herpes simplex virus DNA replication proteins into prereplicative site structures.Herpes simplex ICP27 mutant viruses exhibit reduced expression of specific DNA replication genesCharacterization of ICP6::lacZ insertion mutants of the UL15 gene of herpes simplex virus type 1 reveals the translation of two proteins.Assembly of complete, functionally active herpes simplex virus DNA replication compartments and recruitment of associated viral and cellular proteins in transient cotransfection assays.Immunization against genital herpes with a vaccine virus that has defects in productive and latent infection.Neuron-specific restriction of a herpes simplex virus recombinant maps to the UL5 gene.Unusual regulation of expression of the herpes simplex virus DNA polymerase geneTwo regions of the herpes simplex virus type 1 UL42 protein are required for its functional interaction with the viral DNA polymerase.The six conserved helicase motifs of the UL5 gene product, a component of the herpes simplex virus type 1 helicase-primase, are essential for its function.ND10 protein PML is recruited to herpes simplex virus type 1 prereplicative sites and replication compartments in the presence of viral DNA polymerase.Characterization of nuclear structures in cells infected with herpes simplex virus type 1 in the absence of viral DNA replicationHerpes simplex virus type 1 prereplicative sites are a heterogeneous population: only a subset are likely to be precursors to replication compartments.Herpes simplex virus type 1 DNA cleavage and encapsidation require the product of the UL28 gene: isolation and characterization of two UL28 deletion mutants.
P2860
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P2860
The UL5 gene of herpes simplex virus type 1: isolation of a lacZ insertion mutant and association of the UL5 gene product with other members of the helicase-primase complex.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
The UL5 gene of herpes simplex ...... the helicase-primase complex.
@ast
The UL5 gene of herpes simplex ...... the helicase-primase complex.
@en
type
label
The UL5 gene of herpes simplex ...... the helicase-primase complex.
@ast
The UL5 gene of herpes simplex ...... the helicase-primase complex.
@en
prefLabel
The UL5 gene of herpes simplex ...... the helicase-primase complex.
@ast
The UL5 gene of herpes simplex ...... the helicase-primase complex.
@en
P2860
P1433
P1476
The UL5 gene of herpes simplex ...... the helicase-primase complex.
@en
P2093
P2860
P304
P407
P577
1992-01-01T00:00:00Z